Hi Ernie,
Were you intending to guide with the ASI1600MM camera? Usually we see people using that as an imaging camera and not a guide camera.
If so, the guiding image scale of 0.20"/px is quite extreme. When you setup your equipment profile PHD2 would have recommended 4x binning, and if you had gone with that recommendation you would not have had the star loss problems. To correct this now (assuming you really do intend to use the 1600 as a guide camera) you should create a new equipment profile (Connect Equipment > Manage Profiles > New using Wizard...). Also, for using the 1600 as a guide camera I would highly recommend enabling subframes (brain > camera tab) to reduce the frame download time.
On the other hand if you have a different ZWO camera that you want to use as the guide camera, you would use the camera selection button to select it (see the section Multiple Cameras of the Same Type in the
PHD2 Help under Equipment Connection). Again, I recommend you setup a new equipment profile for the guide camera, but make sure only the guide camera is plugged in (not the 1600) when you set it up. When you have both cameras connected, you can go into the Connect Equipment window and use the camera selection button and select the guide camera -- PHD2 will remember your selection from then on.
Andy