It looks like there are several problems here. But if you want to focus on the pulse-guide command timeout, you should eliminate the ASCOM Device Hub. That’s just an extra layer of software in the communications pipeline to the mount and it shouldn’t be needed for your mount. The Device Hub is really intended for situations where the mount driver isn’t capable of handling more than one attached application at a time. If that isn’t a problem, eliminate the Hub. The PHD2 alert means the mount driver has never reported completion of a previous command to pulse-guide it.
The other major problems include all the camera timeouts you got in the first hour of operation. Did you do something explicitly to fix that? It indicates potential problems in the USB subsystem which can also affect communications with the mount. Another problem is the events that look like this:

All these huge peaks represent very large apparent excursions of the guide star. The most likely source of these problems is the flimsy finder-scope assembly you’re using for guiding. You’re in the unfortunate situation where a mechanical shift of the guide camera by only 3-4 microns (less than 1/10 the thickness of a human hair) results in a guide star excursion of over 6 arc-sec.
I think the first priority should be to resolve any and all USB communication problems in addition to removing the Device Hub and seeing if the pulse-guide timeouts go away. There is an extensive section in the PHD2 manual regarding USB-related problems:
https://openphdguiding.org/man-dev/Trouble_shooting.htm#Problems-_Camera_Timeouts
Good luck,
Bruce
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