Is it possible for Open Ephys GUI to currently interface with the ONIX system, or is there a potential for future compatibility?

[Junying Su]

Hi, I am currently using the ONIX system (with Neuropixels) to perform electrophysiological recordings in freely moving mice. However, I have found that the Bonsai programs for the ONIX system is less convenient for visualizing real-time electrophysiological signals compared to the Open Ephys GUI, which I used previously for recordings in head-fixed mice. The visualization interface in Bonsai is not as user-friendly as that of Open Ephys GUI. I was wondering if Open Ephys GUI can currently detect the ONIX system, or if there are plans to support it in the future. If Open Ephys GUI could support the ONIX system, it would make our work much more convenient. Thank you.

[Josh Siegle]

Hi Junying,

Yes, this is possible now! If you launch the Plugin Installer, you should be able to install the "ONIX Source" plugin. Configuration instructions are available here: https://open-ephys.github.io/gui-docs/User-Manual/Plugins/Onix-Source.html

Note that the plugin is still under development. Feel free to open a GitHub issue if you encounter any bugs, or have any feature requests.

Josh

On Sat, Aug 02, 2025 at 4:44 AM, Junying Su <s2742...@gmail.com> wrote:

Hi, I am currently using the ONIX system (with Neuropixels) to perform electrophysiological recordings in freely moving mice. However, I have found that the Bonsai programs for the ONIX system is less convenient for visualizing real-time electrophysiological signals compared to the Open Ephys GUI, which I used previously for recordings in head-fixed mice. The visualization interface in Bonsai is not as user-friendly as that of Open Ephys GUI. I was wondering if Open Ephys GUI can currently detect the ONIX system, or if there are plans to support it in the future. If Open Ephys GUI could support the ONIX system, it would make our work much more convenient. Thank you.

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