Neuropix-PXI and OneBox plugin v2.0

[Anjal Doshi]

Hi everyone,

Version 2.0 of the Open Ephys GUI's Neuropix-PXI and OneBox plugins are now available via the built-in Plugin Installer.

This update adds support for Neuropixels 2.0 "Quad Base" probes, and includes a number of helpful improvements:

Survey Mode – Quickly generate an activity map across multiple probes in parallel. Survey results are displayed directly in the GUI, or can be downloaded as a JSON file for further analysis.

Enhanced Activity View – The live probe heatmap now includes an option to apply a bandpass filter and/or common average reference to the data before it's displayed. The probe browser also includes additional information, such as the distance of each electrode from the probe tip.

Broken Shank Detection – For multi-shank probes, the plugin automatically detects broken shanks. These are highlighted in pink in the probe browser. Shanks that remain yellow can still be used.

Note: This version requires a basestation firmware update (unless you’re already using the latest version of SpikeGLX).

📘 View the updated documentation here and here.

If you’ll be attending SfN, come visit us at the Open Ephys or Neuropixels booths—we’d love to hear your feedback and show you the new features in action!

Best,
Anjal and Josh

[Anjal Doshi]

A correction to the previous update: individual broken shanks can be detected in the latest version of the plugin, but there is still no guarantee that they will be programmed correctly. IMEC is working on a fix for this, but for now probes with any broken shanks should be used with caution.

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