Actually, there *is* a way to do what you asked, but it requires specific settings.
When you "delete" a sample, the patterns that used the sample still point to that slot. So if you load a sample in the exact same spot, then patterns will still point to it.
The issue is that when you "move" a sample, the patterns that use the sample will "follow" where that sample moved.
I'm not being very clear, but try this:
2) View the patterns tab.
3) Select pattern "A01 - House1".
4) Select the "Parts" tab in the "Selected Patterns" section.
5) Confirm that Drum1 points to sample BD-3
6) Now click on the samples tab
7) Delete sample "002 - BD-3"
8) Load any MONO sample from your hard drive
9) Follow steps 2-5, but confirm that the pattern is now pointing to the sample you just loaded
The problem is when you "move" samples, the patterns will follow the move. That is, unless I make the preference I spoke about in my last email "editable".
Hope that makes sense.
Take care!