OncoKB New Data Release - December 21, 2023

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Dec 28, 2023, 2:47:27 PM12/28/23
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Data Release v4.13 

December 21, 2023


Dear OncoKB user,


Happy Holidays! Here at OncoKB we are celebrating a year of milestones!


2023 has been a remarkable year for us! We have had 13 successful data releases and the launch of our newest data resource, the FDA-Approved Oncology Therapies page, which includes an up-to-date, comprehensive classification of all FDA-approved oncology drugs. Additionally, OncoKB’s second manuscript, "Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer", and our collaborative review, "Precision Oncology: 2023 in Review", were published in Cancer Discovery, thus marking significant strides in our growth as a precision oncology resource worldwide.


Thank you for your unwavering support. Together, we're making a difference in the world of cancer research. Here's to continuing our shared mission in the new year!


Warm wishes from the OncoKB Team

What's New

 


  • We have replaced the “Precision Oncology Therapies” page with “FDA-Approved Oncology Therapies”, which includes classification of which oncology therapies are considered “precision oncology therapies”  


  • Updated therapeutic implications - New alterations with a level of evidence

    •  Level R2Cetuximab and Panitumumab added as investigational resistance treatments for EGFR S464LG465EG465RV441DV441G and S492R in colorectal cancer based on identification of these mutations in patients with colorectal cancer who progressed on anti-EGFR therapy (PMID: 2942352129196463)


  • Addition of 13 new genes:

EMSY FGF23 FRS2 GABRA6 GATA4 KEL PIK3C2B PRKDC QKI RANBP2 SOX10 STAT4 TAF1


We're Here to Help

As always, don’t hesitate to reach out if you have comments, questions or suggestions. We love to hear from you. You can reach us at con...@oncokb.org




--
The OncoKB Team
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