Newest OncoKB updates: July 28, 2023
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Jul 28, 2023, 3:00:27 PM7/28/23
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Dear OncoKB user,
Here are the latest OncoKB updates:
Here are the latest OncoKB updates:
July 28, 2023Data version: v4.7
- Updated therapeutic implications - addition of therapies for variants with a level of evidence
Gene Mutation Cancer Type Current Level of Evidence Drug(s) Already in OncoKB™ Newly Added Drug(s) Evidence FLT3 Internal Tandem Duplications (ITD) Acute Myeloid Leukemia 1 Gilteritinib
(Level 1),
Midostaurin + High Dose Chemotherapy
(Level 1),
Crenolanib
(Level 3A),
Quizartinib
(Level 3A) Quizartinib
(Promoted to Level 1) FDA-approval of Quizartinib; PMID: 37116523
- Addition of 14 new genes:
- Updated therapeutic implications - addition of therapies for variants with a level of evidence
Gene Mutation Cancer Type Current Level of Evidence Drug(s) Already in OncoKB™ Newly Added Drug(s) Evidence FLT3 Internal Tandem Duplications (ITD) Acute Myeloid Leukemia 1 Gilteritinib
(Level 1),
Midostaurin + High Dose Chemotherapy
(Level 1),
Crenolanib
(Level 3A),
Quizartinib
(Level 3A)Quizartinib
(Promoted to Level 1)FDA-approval of Quizartinib; PMID: 37116523 - Addition of 14 new genes:
As always, don’t hesitate to reach out if you have comments, questions or suggestions. We love to hear from you.
The OncoKB Team
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