setting the FC cutoff for differential expression analysis

[Shahab Mirshahvaladi]

hello again!

I wish we could set the Fold Change in differential analysis instead of logFC as there are limited options in the menu, making it hard to choose the right cutoff for next steps. 

Working with TMT proteomics, and the platform for generating proteomics data, our group usually sets the cutoff at |FC|>1.2 but this is not obviously possible even in the Beta version. converting the LogFC values, we have the following options in the platform:

log FC        FC
  1                2
0.5              1.41421
0.2              1.1487
0.1              1.07177

To make the package more versatile, can you please add 0.263034 which represents log 1.2 to current logFC values? or add a continuous scroll bar somewhere in the options? 

Cheers,

Shahab

  

[Mauro Masiero]

Dear Shahab,

Thanks for your suggestion, we are currently not planning in adding this feature, as not many users have mentioned this. We will keep it in out expansion list as this is an interesting future implementation! I placed the enhancement here: https://github.com/bigomics/omicsplayground/issues/312. Consider supporting us via a subscription so we promote the development of this feature in the future!

Best,

Mauro,

[Shahab Mirshahvaladi]

Thanks Mauro. I saw the conversation in github. sounds good.