Unit 4 Biostatistics

[Claribel Lizama]

TheBiostatistics Unit at the Feinstein Institutes for Medical Research supports investigators in the design, implementation, data management, statistical analysis, and publication of basic science and clinical research studies. The team applies statistical and mathematical methods to the analysis of research data and develops new methods to address complex research problems.

Additionally, members of the department teach biostatistics, epidemiology, and research study design to faculty, fellows, residents, medical students, and other staff throughout the organization and its affiliated medical schools. The Biostatistics Unit is unique in that it is one of only a handful of biostatistics departments in the U.S. that is administratively part of a healthcare system that is not a medical school or university.

Members of the Biostatistics Unit are routinely authors or co-authors on many scientific publications and presentations. Papers are presented by staff at a variety of scientific and statistical meetings.

The Biostatistics and Data Management Scientific Core Unit assists research teams with biostatistics, bioinformatics, data management, and scientific computing. The Core Unit works with investigators on study design, implementation, and data analysis to support research activities across basic science, animal, and human studies in nutrition, with an emphasis on rigor, reproducibility and transparency.

The Core Unit supports development of statistical analysis plans to ensure appropriate data analysis methods, proper handling of missing data and multiple testing issues, and appropriately powered studies. Special care is taken to address statistical issues that arise in nutrition studies, such as selection of appropriate control diets and minimization of measurement error. The Core Unit provides bioinformatics support for targeted and untargeted metabolomics, machine learning approaches (random forest and neural networks), genomic and metagenomics sequencing, and integrative omics analyses.

The Core Unit assists investigators with implementation, monitoring and adherence to data management plans (adhering to NIH and USDA requirements) including electronic data capture (REDCap and LabArchives) as well as clinical trials registration and summary results submission to ClinicalTrials.gov per the Final Rule issued by the U.S. DHHS and the NIH. Support is provided for the creation, maintenance, and archival of databases that meet all federal requirements.

We welcome partnering with HNRCA investigators on biostatistics and data management needs. See the HNRCA Biostatistics and Data Management Core Services table which lists the services available and indicates whether they are HNRCA-supported services (no cost recovery) or services provided through cost recovery.

The unit includes Ph.D.-level and masters-level biostatisticians. Through our collective expertise and capabilities, we can successfully support a wide range of clinical and biological studies through application of common and advanced statistical approaches. We also collaborate with faculty from the Department of Public Health Sciences for projects that deploy integrated biostatistical and informatics expertise.

Grant applications, manuscripts and presentations that involve quantitative methods are generally more competitive when a biostatistician is involved. You will benefit most from the Unit's services when you consider us as your partners in research and get us involved early in your project activities. The Biostatistics Unit is support by the School of Medicine and thus SOM investigators are our priority. Ongoing statistical support for other academic units may be available, subject to a mutually acceptable memorandum of understanding.

The Biostatistics Unit provides statistical support as a partner in your research. Whether it be collaboration on grants, manuscripts, education, or data analysis, our biostatisticians and data analysts are prepared to assist you in your research activities. Requests for consultations need to be accompanied by the approval of your Department Chair and/or Assistant/Associate Dean(s) of Research.

Our Biostatistics Unit is expanding to meet the needs of the School of Medicine and our collaborators across the University of Missouri Campus. We are pleased to host these innovative speakers as potential new team members. These presentations will be relevant for health researchers, trainees and clinicians.

Our Biostatistics Unit plays a critical role in research capacity building at the School of Medicine as well as other Faculties and Schools at the University of Missouri. This Assistant Professor position offers a competitive salary with start-up funds, ongoing professional development funds and opportunities for promotion as well as relocation support.

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The authorship list on a scientific publication identifies those responsible for the integrity of results and those to credit for the findings. Co-authorship is appropriate when the biostatistician or data analyst makes a substantial contribution to the design, analysis or interpretation of results. Assignment of authorship is a matter of scientific integrity and is independent of funding.

Please visit our blog for announcements of appointments, promotions, and other milestones. See also the graduate program news feed, where we celebrate our students' dissertation defenses, publications, and more.

Our department members (including students) and alumni organize and present lectures and workshops around the world, including at JSM 2024 in Portland (OR). See our upcoming presentations page for a glimpse of what's on deck, including Panpan Zhang in Blowing Rock (NC) and Boston.

Vanderbilt Health recognizes that diversity is essential for excellence and innovation. We are committed to an inclusive environment where everyone has the chance to thrive and to the principles of equal opportunity and affirmative action. EOE/AA/Women/Minority/Vets/Disabled

In this essential role, Dr. Long will support the academic and professional growth of DBEI faculty members at all stages of their careers. His new responsibilities will include enhancing mentorship opportunities for junior faculty members; providing guidance on career advancement and tenure processes; identifying and allocating University resources to support professional development; and cultivating a collaborative research environment where every DBEI faculty member is empowered to reach their fullest potential.

Dr. Long will also partner with other DBEI leaders to foster diversity, equity, inclusion, and belonging within the department through responsive recruitment and retention initiatives and paying particular attention to the career development of and unique challenges faced by faculty members from underrepresented groups.

July 1, 2024. Please join us in welcoming Jiayin Zheng, PhD as an Assistant Professor of Biostatistics to the department, effective July 1, 2024. Dr. Zheng earned a BS in Statistics from the Department of Mathematics at Zhejiang University in Hangzhou, China (2009) and a PhD in Statistics from the Department of Probability and Statistics at Peking University in Beijing, China (2015). He worked as a postdoctoral associate with Dr. Shein-Chung Chow at Duke University (2016-2017), and then as a postdoctoral research fellow with Dr. Li Hsu at the Fred Hutchinson Cancer Research Center (2017-2019) before being appointed at a Staff Scientist in the Biostatistics Program in the Public Health Sciences Division there.

Elizabeth Nesoff, PhD, MPH discusses her recently published study in the Leonard Davis Institute of Health Economics (LDI) blog investigating neighborhood features that were correlated with fatal opioid overdoses among the homeless population in New York City. Dr. Nesoff uses these discoveries to make important policy recommendations with respect to targeted outreach and other interventions.

Jeffrey Morris, PhD and Jeffrey Gerber, MD, PhD, MSCE collaborated with researchers to examine measles serostatus among pregnant persons about to give birth and whether rubella serostatus, which is routinely assessed during pregnancy, can serve as a proxy for measles serostatus.

Welcome to the Department of Biostatistics at the University of North Carolina. We are home to some of the finest minds in this ever-growing and changing field, at one of the leading universities in the nation. As Chair and professor, I am privileged to collaborate with our faculty on one of the most important undertakings we can contribute to society - that of training new, brilliant leaders to be the future of biostatistics.

The Department of Biostatistics faculty are internationally recognized leaders in biostatistics research and training, with particular expertise in machine learning, precision medicine, clinical trials, high dimensional data, genomics, Bayesian methods, causal inference, and many other areas.

In 1949, Gertrude Cox, MS, helped establish the Department of Biostatistics in the UNC-Chapel Hill School of Public Health, selecting her former student, Bernard Greenberg, PhD, to lead the new department. Dr. Greenberg pioneered efforts to establish the practice of cooperative multicenter trials, changing the course of practice for the evaluation of new drugs.

That tradition of statistical innovation continues in a program led by Lisa LaVange, PhD, professor of biostatistics. Today, the biostatistics department is the statistical home for many studies in the UNC schools of medicine and nursing, and provides statistical support for the UNC Lineberger Comprehensive Cancer Center and the NC Translational and Clinical Sciences Institute (NC TraCS).

Drs. Lisa LaVange, Joseph Ibrahim, Donglin Zeng and Ethan Alt were recognized with the Statistical Partnerships Among Academe, Industry, and Government (SPAIG) Award for "outstanding and impactful research in clinical trials and outcomes research, setting the standard for academic-industry-government collaborations."

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