[Obo-diffs] New mp Definition Changes
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 22 Oct 2017:
MP:0000107 : abnormal frontal bone morphology
OLD: any structural anomaly of the bone forming the forehead and roof of the eye orbit
NEW: any structural anomaly of the single bone forming the forehead and roof of the eye orbit
MP:0000109 : abnormal parietal bone morphology
OLD: any structural anomaly of the curved bone forming part of the vault of the cranium
NEW: any structural anomaly of either of a pair of membranous bones of the roof of the skull located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium
MP:0000229 : abnormal megakaryocyte differentiation
OLD: atypical production of or inability to produce of a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm
NEW: atypical production of or inability to produce the giant 50 to 100 micron diameter cells with greatly lobulated nuclei found in the bone marrow; mature blood platelets are released from their cytoplasm
MP:0002239 : abnormal nasal septum morphology
OLD: any structural anomaly of the structure that separates the two nasal cavities
NEW: any structural anomaly of the dividing wall that runs down the midline of the nose separating the two nasal cavities, each of which ends in a nostril; it is formed by the septal nasal cartilage, parts of skull bones (ethmoid bone; vomer), and membranous parts
MP:0002417 : abnormal megakaryocyte morphology
OLD: any structural anomaly of a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm
NEW: any structural anomaly of the giant 50 to 100 micron diameter cells with greatly lobulated nuclei found in the bone marrow; mature blood platelets are released from their cytoplasm
MP:0004033 : supernumerary teeth
OLD: occurrence of more than the usual number of teeth
NEW: presence of a supernumerary, i.e., extra, tooth or teeth
OLD: abnormal posterior-shifted positioning of the jaws, particularly the mandible, relative to the facial skeleton and soft tissues
NEW: abnormal posterior-shifted positioning of the upper or lower jaw relative to the facial skeleton and soft tissues; a type of malocclusion, that is, misalignment of the teeth caused by abnormal positioning of the jaws; the mandible is more frequently affected than the maxilla
MP:0004418 : small parietal bone
OLD: reduced size of the curved bone forming part of the vault of the cranium
NEW: reduced size of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium
MP:0004419 : absent parietal bone
OLD: absence of the curved bone forming part of the vault of the cranium
NEW: absence of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium
MP:0004420 : parietal bone hypoplasia
OLD: underdevelopment or reduced size, usually due to a reduced number of cells, in the curved bone forming part of the vault of the cranium
NEW: underdevelopment or reduced size, usually due to a reduced number of cells, of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium
MP:0004421 : enlarged parietal bone
OLD: increased size of the curved bone forming part of the vault of the cranium
NEW: increased size of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium
OLD: a congenital defect in which the two orbits are united to form a single cavity containing one eye
NEW: a congenital defect characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities; cyclopia is a rare form of holoprosencephaly that typically presents with a median single eye or a partially divided eye in a single orbit, absent nose, and a proboscis above the eye
MP:0008253 : absent megakaryocytes
OLD: absence of giant cells 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm
NEW: absence of the giant 50 to 100 micron diameter cells with greatly lobulated nuclei found in the bone marrow; mature blood platelets are released from their cytoplasm
MP:0008254 : increased megakaryocyte cell number
OLD: greater number of giant cells 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm
NEW: greater number of the giant 50 to 100 micron diameter cells with greatly lobulated nuclei found in the bone marrow; mature blood platelets are released from their cytoplasm
MP:0008255 : decreased megakaryocyte cell number
OLD: reduced number of giant cells 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm
NEW: reduced number of the giant 50 to 100 micron diameter cells with greatly lobulated nuclei found in the bone marrow; mature blood platelets are released from their cytoplasm
MP:0012155 : abnormal optic pit morphology
OLD: any structural anomaly of the depression found on each side of the end of the neural ectoderm (or neural tube) of the embryo; the pit deepens to form the optic vesicle
NEW: any structural anomaly of either of the two pits that appear bilaterally in the region destined to become the forebrain as the cranial neural folds fuse; these optic pits or sulci continue to deepen laterally and bulge from the two sides of the forebrain to become the optic vesicles
MP:0013815 : abnormal digastric muscle morphology
OLD: any structural anomaly of the small suprahyoid muscle located below the body of the mandible, and extending, in a curved form, from the mastoid notch to the symphysis menti; it consists of two muscular bellies, an anterior and a posterior belly, united by an intermediate rounded tendon attaching to the hyoid bone through a fibrous loop
NEW: any structural anomaly of the small suprahyoid muscle located below the body of the mandible, and extending, in a curved form, from the mastoid notch to the symphysis menti; it consists of two muscular bellies, an anterior and a posterior belly, united by an intermediate rounded tendon attaching to the hyoid bone through a fibrous loop; the two bellies have different embryological origins and are supplied by different cranial nerves
MP:0030049 : prominent forehead
OLD: forward prominence of the entire forehead, due to protrusion of the frontal bone
NEW: forward prominence of the entire forehead, due to protrusion of the frontal bone; not to be confused with frontal bossing
MP:0030179 : abnormal oral epithelium morphology
OLD: any structural anomaly of the stratified squamous epithelium that forms part of the oral mucosa and lines the inner aspect of the oral cavity; depending on the mouth region, the epithelium may be non-keratinized or keratinized
NEW: any structural anomaly of the stratified squamous epithelium that forms part of the oral mucosa and lines the inner aspect of the oral cavity; depending on the mouth region, the epithelium may be non-keratinized or keratinized; non-keratinized squamous epithelium covers the soft palate, inner lips, inner cheeks, and the floor of the mouth, and ventral surface of the tongue; keratinized squamous epithelium is present in the attached gingiva and hard palate as well as areas of the dorsal surface of the tongue
MP:0030184 : abnormal zygomaticus muscle morphology
OLD: any structural anomaly of the zygomaticus major and/or minor facial muscles that originate from the body of the zygoma and pass downwards to insert into the corner of the mouth and lateral aspect of the upper lip, respectively
NEW: any structural anomaly of the zygomaticus major and/or minor facial muscles that originate from the body of the zygoma and pass downwards to insert into the corner of the mouth and lateral aspect of the upper lip, respectively; these muscles receive their nerve supply on their deep surface from the zygomatic and buccal branches of the facial nerve and lift the corners of the mouth
Signed,
The mp File Watching Daemon
Ontology report info
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 23 Oct 2017:
MP:0000100 : abnormal ethmoid bone morphology
(was abnormal ethmoidal bone morphology)
OLD: any structural anomaly of the midline facial bone that encloses the nasal cavity
NEW: any structural anomaly of the single midline facial bone that separates the nasal cavity from the brain, located at the roof of the nose between the two orbits; it is cubical in shape, relatively lightweight because of its spongy construction, and contributes to the anterior cranial fossa
MP:0000101 : absent ethmoid bone
(was absent ethmoidal bone)
OLD: missing midline facial bone that encloses the nasal cavity
NEW: missing the single midline facial bone that separates the nasal cavity from the brain, located at the roof of the nose between the two orbits; it is cubical in shape, relatively lightweight because of its spongy construction, and contributes to the anterior cranial fossa
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 24 Oct 2017:
MP:0004423 : abnormal temporal bone squamous part morphology
(was abnormal squamosal bone morphology)
OLD: any structural anomaly of the thin, plate-like part of the temporal bone
NEW: any structural anomaly of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault
MP:0004899 : absent temporal bone squamous part
(was absent squamosal bone)
OLD: absence of the thin, plate-like part of the temporal bone
NEW: absence of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 25 Oct 2017:
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 26 Oct 2017:
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 27 Oct 2017:
OLD: reduced length of the anterior and interior portion of the maxilla
NEW: length reduction or truncation of the anterior and interior portion of the maxilla
OLD: a type of arthritis that results in the breakdown and eventual loss of the auricular cartilage of one or more joints
NEW: a type of arthritis that results in the breakdown and eventual loss of the articular cartilage of one or more joints
MP:0004871 : premaxilla hypoplasia
OLD: underdevelopment or reduced size, usually due to a reduced number of cells, in the anterior and interior portion of the maxilla
NEW: underdevelopment or reduced size, usually due to a reduced number of cells, of the anterior and interior portion of the maxilla
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 28 Oct 2017:
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 31 Oct 2017:
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 1 Nov 2017:
MP:0000081 : premature cranial suture closure
(was premature suture closure)
OLD: early fusion of the bones of the skull
NEW: early closure of one or more of the joints (sutures) between the bones of the skull; can cause alterations in head shape, facial features, brain growth and, in rare cases, damage to the brain due to increased pressure inside the skull
MP:0010743 : delayed cranial suture closure
(was delayed suture closure)
OLD: late onset of the fusion of the bones of the skull
NEW: late onset of closure of one or more of the joints (sutures) between the bones of the skull
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 2 Nov 2017:
MP:0003841 : abnormal lambdoid suture morphology
(was abnormal lambdoidal suture morphology)
OLD: any structural anomaly of the dense, fibrous connective tissue joint between the parietal bones and the occipital bone
NEW: any structural anomaly of the dense, fibrous connective tissue joint between the superior border of the occipital bone and the posterior borders of the right and left parietal bones
MP:0003844 : abnormal squamoparietal suture morphology
(was abnormal squamo-parietal suture morphology)
OLD: any structural anomaly of the dense, fibrous connective tissue joint between the squamous portion of the temporal bones with the parietal bones
NEW: any structural anomaly of the dense, fibrous connective tissue joint between the squamous part of the temporal bone and the inferior aspect of the parietal bone; posteriorly, the squamous suture becomes the parietomastoid suture where the mastoid process articulates with the parietal bone; anteriorly, the squamous suture extends towards the pterion
MP:0030029 : wide cranial sutures
OLD: an abnormally increased width of any of the cranial sutures for age-related norms, generally resulting from delayed suture closure
NEW: an abnormally increased width of one or more cranial sutures for age-related norms, generally resulting from delayed suture closure
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 7 Nov 2017:
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 9 Nov 2017:
MP:0003842 : abnormal metopic suture morphology
OLD: any structural anomaly of the dense, fibrous connective tissue joint between the frontal bone from the sagittal suture to the root of the nose; it is visible in neonates and juveniles, but it is frequently obliterated in some adult organisms
NEW: any structural anomaly of the dense, fibrous connective tissue joint between the frontal bones from the sagittal suture to the root of the nose; it is visible in neonates and juveniles, but it is frequently obliterated in some adult organisms; in mice and rats, the posterior frontal (PF) suture, situated between the frontal bones, is analogous to the human metopic suture; the anterior landmark for the PF suture is the jugum limitans; the posterior landmark for the PF suture is the bregma
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 11 Nov 2017:
MP:0002248 : abnormal sphenoid sinus morphology
OLD: any structural anomaly of the paired evaginations of the mucous membrane of the nasal cavity into the air space located within the sphenoid bone, and which communicates with the upper posterior nasal cavity or sphenoethmoidal recess
NEW: any structural anomaly of the most posterior paranasal sinus located in the sphenoid bone near the optic nerve and the pituitary gland on the side of the skull; it drains into the sphenoethmoidal recess superior to the superior concha; the sinus is divided into right and left parts by a bony septum
jen...@ladle.lbl.gov
The definitions of the following mp terms changed as of 14 Nov 2017:
MP:0008430 : short temporal bone squamous part
(was short squamosal bone)
OLD: length reduction of the thin, platelike part of the temporal bone
NEW: length reduction of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault
MP:0030121 : small temporal bone squamous part
(was small squamosal bone)
OLD: reduced size of the thin, plate-like part of the temporal bone
NEW: reduced size of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault
MP:0030122 : temporal bone squamous part hypoplasia
(was squamosal bone hypoplasia)
OLD: underdevelopment or reduced size, usually due to a reduced number of cells, of the thin, plate-like part of the temporal bone
NEW: underdevelopment or reduced size, usually due to a reduced number of cells, of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault