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Paris (English: / ˈ p ær ɪ s /; French pronunciation: ⓘ) is the capital and most populous city of France. With an official estimated population of 2,102,650 residents as of 1 January 2023 in an area of more than 105 km 2 (41 sq mi), Paris is the fifth-most populated city in the European Union and the 30th most densely populated city in the world in 2022. Since the 17th century, Paris has .

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The Île-de-France (/ ˌ iː l d ə ˈ f r ɒ̃ s /, French: [il də fʁɑ̃s] ⓘ; literally "Isle of France") is the most populous of the eighteen regions of France, with an official estimated population of 12,271,794 residents on 1 January 2023. Centred on the capital Paris, it is located in the north-central part of the country and often called the Paris Region (French: Région parisienne .

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Paris, the cosmopolitan capital of France, is one of the largest agglomerations in Europe, with 2. 2 million people living in the dense central city in 2022, 10 million people in the Métropole du Grand Paris and almost 13 million people living in the metropolitan area. Overview. Map. Directions.

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The Development of GHRP-6. In 1982, the natural hormone "Growth Hormone Releasing Hormone" (GHRH) was identified after a prolonged search. Soon, researchers discovered that those GH-Releasing Peptides (specifically GHRP-6 & GHRP-2) followed a mode of action which bound them to and was mediated through receptors different from those for GHRH. . Furthermore, researches discovered that these GH .

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Île-de-France. Île-de-France is the compact region immediately surrounding Paris. As such, the region includes all of the metropolis, from the great French capital itself through the gritty inner banlieue right out to now far-flung suburbs and exurbs, together with several large surrounding towns that form part of the greater conurbation.

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It can be used to study the dependency of GHSR-1a signalling mediated by acylated ghrelin. [5] [D-Lys 3 ]-GHRP6 (growth hormone releasing peptide 6) induces the secretion of growth hormone (GH). In the membrane of clonal GC somatotropes, this peptide elevates the number of functional voltage-gated Ca 2+ and Na + channels.

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