New Research July 2021- transfer of fibromyalgia from Human to Lab Animal, IgG antibody mechanism

[Joseph Arabasz MD]

Subject: New Research July 2021- transfer of fibromyalgia from Human to Lab Animal, IgG antibody mechanism

 

Dear Topica,

                                                                                                                                                                    I hope this note finds You well                                                                                                                                                   

FYI-

     Was surprised to find this Research Article since some have described fibromyalgia and CFS (chronic fatigue syndrome) as one and the same disease process

     Perhaps the severe hypoxia seen at the capillary level and unusual new products of metabolism, etc which would elicit an antigen response, would then react with other usually non-allergenic structures of the body causing inflammation and discomfort

     chronic, severe discomfort appears to cause fatigue and irritability

     fibromyalgia is part of the constellation of symptoms seen with the CFS (chronic fatigue syndrome) spectrum of diseases, eg CFIDS (chronic fatigue immune deficiency), myalgic encephalomyelitis/chronic fatigue syndrome aka ME/CFS, &c

     Some are of the opinion that the CFS and PTSD are essentially the same disease

     Have seen Medical Journal comments that some antibodies last years in Humans, vs weeks with these Lab Animals since the IgG used was foreign to them, which might make for a prolonged Recovery

Best wishes always

Thank you for your assistance with this matter

Cordially,

Joseph W Arabasz MD

S/P USAF, Top Secret 1964-69

University of Colorado at Boulder 1972, CU School of Medicine '75, '77, '83

Past Division Chairman, Anesthesiology, Cook County Hospital, Chicago, Illinois

Past Chairman, Respiratory Therapy, Cook County Hospital, Chicago

Diplomate ABA

Mensa

Sigma Xi, The Professional Science Research Society

http://www.SigmaXi.org

PO Box 6939

Denver, CO 80206

USA

720-364-2265

https://groups.google.com/g/nutrition-jwamd

https://groups.google.com/forum/#!categories/nutrition-jwamd

http://groups.google.com/group/nutrition-jwamd/topics

http://www.topica.com/lists/joseph...@topica.com (2001-2014 site closed/open)

-------------------------------------------------------------------------------------------------------------------------

Jul 27, 2021 NEJM Review

fibromyalgia Symptoms Can Be Transferred from Humans to Lab Animals

Infusion of immunoglobulin G from fibromyalgia patients caused fibromyalgia-like symptoms in Lab Animals

IgG transfer of fibromyalgia symptoms from patients to Lab Animals

Published July 1, 2021

Introduction

Fibromyalgia syndrome (FMS) is a chronic pain condition 

characterized by widespread pain, augmented pain sensitivity to

mechanical pressure and cold temperatures, as well as

fatigue and emotional distress. The prevalence of FMS is at

a couple percent of the Population, and approximately 

80% of FMS patients are women

     The prevalence rises to 10%–30% among patients diagnosed

with autoimmune rheumatological conditions, and FMS is

thus one of the most common chronic pain conditions. The etiology 

and pathophysiology of FMS are not completely understood