"Understanding B12" - 90% of vegans deficient of that Essential Vitamine
Joseph Arabasz MD
Dear Topica,
I hope this note finds You well
Mass action absorption explains the large dose recommendations for B12 deficiency
The most observed response after the parenteral administration of B12 (IM hypodermic) is a feeling of wellness, interpreted as anti-fatigue
Best wishes always
Thank you for your assistance with this matter
Cordially,
S/P USAF, Top Secret 1964-69
University of Colorado at Boulder 1972, CU School of Medicine '75, '77, '83
Past Division Chairman, Anesthesiology, Cook County Hospital, Chicago, Illinois
Past Chairman, Respiratory Therapy, Cook County Hospital, Chicago
Diplomate ABA
Mensa
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Understanding Vitamin B12- 90% of vegans deficient
First Published June 20, 2012
Abstract
Vitamin B12 (B12) is essential in activating folate needed in DNA synthesis. Inadequate intake results in the impairment of nerve transmission and inadequate synthesis of erythrocytes and other hematological cells.
Separate mechanisms of B12 absorption exist, a receptor-mediated endocytosis that occurs in the distal ileum and the mass-action pharmacologic mechanism.
The recommended dietary allowance for B12 for adults issued by the Institute of Medicine is 2.4 µg/d. B12 is only found in meats and other foods of animal origin. B12 deficiency is widespread. Two main causes of deficiency include inadequate absorption and intake. Elderly and vegetarians are at highest risk for deficiency. Prevalence of deficiency ranges from 7% of the US population 3 years and older to 90% among vegans. The best way to assess deficiency is by using methylmalonic acid. Populations at risk could benefit from using B12 supplements and from fortification of flour
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Vol 7, Issue 1, 2013
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