Emu Os V1.0

[Salvador Baltimore]

APIsets on the v1.0 endpoint ( ) have reached general availability (GA), and have gone through a rigorous review-and-feedback process with customers to meet practical, production needs. Updates to APIs on this endpoint are additive in nature and don't break existing app scenarios.

Version 1.0 of the Standard for Exchange of Nonclinical Data Implementation Guide: Animal Rule (SENDIG-AR) describes how to represent data for studies submitted under FDA regulations commonly known as the Animal Rule. The Animal Rule provides a regulatory mechanism for the approval of drugs and licensure of biological products when human efficacy studies are not ethical or feasible.

SENDIG-AR v1.0 is based upon, and should be used in close concert with, Version 1.8 of the Study Data Tabulation Model (SDTM) and Version 3.1 of the CDISC Standard for Exchange of Nonclinical Data Implementation Guide (SENDIG). Although the SENDIG v3.1 is based on SDTM v1.5, any data submitted under the Animal Rule should follow the conventions used in this implementation guide, and be based on SDTM v1.8.

The stable release of the SLSA 1.0 Build Track lowers the barrier of entry for improvements, helps you focus efforts on improving your build, and reduces the chances of tampering across a large swath of the supply chain.

At IBM, belief in the power of Open Innovation is driving our current actions and future plans. That is why we have been actively contributing to the Supply chain Levels for Software Artifacts (SLSA) v1.0 specification. By openly collaborating with the OpenSSF community to provide build integrity clarity, package consistency, and adopt-ability at scale, we are certain this framework will help software developers restrict tampering, improve integrity, and better secure packages and infrastructure in software supply chains.

As we continue to enhance the security of how npm packages are built, the SLSA framework has served as a launchpad for us in determining what capabilities to provide. It has been instrumental in moving forward the security of open source packages in a way that makes sense for users, open source maintainers, and vendors.

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The International Wheat Genome Sequencing Consortium is pleased to announce that the first version of the reference sequence of the bread wheat variety Chinese Spring (IWGSC RefSeq v1.0) is now available with annotation of genes, non-coding RNAs and transposable elements at the IWGSC sequence repository hosted by URGI-INRA .

The pre-publication data are being made available under the IWGSC general data access agreement which is consistent with the Toronto Agreement and that grants the IWGSC the right to publish the first global analyses of the data. This includes descriptions of whole chromosome or genome-level analyses of genes, gene families, repetitive elements, and comparisons with other organisms.

The IWGSC RefSeq v1.0 annotation includes gene models generated by integrating predictions made by INRA-GDEC using Triannot and PGSB using their customised pipeline (previously MIPS pipeline). The integration was undertaken by the Earlham institute (EI), who have also added UTRs to the gene models where supporting data are available. Gene models have been assigned to high confidence (HC) or low confidence (LC) classes based on completeness, similarity to genes represented in protein and DNA databases and repeat content. The automated assignment of functional annotation to genes has been generated by PGSB based on AHRD parameters. In addition, annotated transposable elements (TEs) and non-coding RNAs are available. More information about the annotation data is provided in README files from the IWGSC repository hosted on the URGI Sequence Repository .

Jan. 2017 notice:

The International Wheat Genome Sequencing Consortium is pleased to announce that the first version of the reference sequence of the bread wheat variety Chinese Spring (IWGSC RefSeq v1.0) is now available at the IWGSC sequence repository hosted by URGI-INRA ( -urgi.versailles.inra.fr/Seq-Repository/Assemblies)

With the addition of the resources that have been developed by IWGSC members over the past few years, the quality of the assembly increased substantially. When compared with IWGSC WGA v0.4, the chromosomal scaffold/ superscaffold N50 increased from 7.0 Mb to 22.8 Mb.

Earlier Notice:

The IWGSC is pleased to announce that the Genome Assembly (IWGSC WGA) of bread wheat, *T. aestivum* cv Chinese Spring (ERGE 2135), based on Illumina short sequence reads assembled with NRGene's DeNovoMAGICTM software is now available at the IWGSC sequence repository hosted by URGI-INRA.

The data are being made available before publication in accordance with the Toronto Agreement under which the IWGSC reserves the right to publish the first global analyses of the data. This includes descriptions of whole chromosome or genome-level analyses of genes, gene families, repetitive elements, and comparisons with other organisms.

The Falcon 9 v1.0 was the first member of the Falcon 9 launch vehicle family, designed and manufactured by SpaceX in Hawthorne, California. Development of the medium-lift launcher began in 2005, and it first flew on June 4, 2010. The Falcon 9 v1.0 then launched four Dragon cargo spacecraft: one on an orbital test flight, then one demonstration and two operational resupply missions to the International Space Station under a Commercial Resupply Services contract with NASA.

The vehicle was retired in 2013 and replaced by the upgraded Falcon 9 v1.1, which first flew in September 2013. Of its five launches from 2010 to 2013, all successfully delivered their primary payload, though an anomaly led to the loss of one secondary payload.

The Falcon 9 v1.0 first stage was used on the first five Falcon 9 launches, and powered by nine SpaceX Merlin 1C rocket engines arranged in a 3x3 pattern. Each of these engines had a sea-level thrust of 556 kN (125,000 pounds-force) for a total thrust on liftoff of about 5,000 kN (1,100,000 pounds-force).[3]

The upper stage was powered by a single Merlin 1C engine modified for vacuum operation, with an expansion ratio of 117:1 and a nominal burn time of 345 seconds. For added reliability of restart, the engine has dual redundant pyrophoric igniters (TEA-TEB).[3] The second stage tank of Falcon 9 is simply a shorter version of the first stage tank and uses most of the same tooling, material and manufacturing techniques. This saves money during vehicle production.[3]

The Falcon 9 v1.0 interstage, which connects the upper and lower stage for Falcon 9, is a carbon fiber aluminum core composite structure. Reusable separation collets and a pneumatic pusher system separate the stages. The stage separation system had twelve attachment points (later reduced to just three in the v1.1 launcher).[8]

SpaceX uses multiple redundant flight computers in a fault-tolerant design. Each Merlin engine is controlled by three voting computers, each of which has two physical processors that constantly check each other. The software runs on Linux and is written in C++. For flexibility, commercial off-the-shelf parts and system-wide "radiation-tolerant" design are used instead of radiation-hardened parts.[9]

Four Draco thrusters were to be used for at least the second revision of the Falcon 9 v1.0 rocket second-stage as a reaction control system.[10] It is unknown whether Falcon 9 ever flew with these thrusters; the second revision of Falcon 9 v1.0 was replaced with the Falcon 9 v1.1, which used nitrogen cold gas thrusters.[11] The thrusters were used to hold a stable attitude for payload separation or, as a non-standard service, were also designed to be used to spin up the stage and payload to a maximum of 5 rotations per minute (RPM),[10] although none of the five flown missions had a payload requirement for this service.

While SpaceX spent its own money to develop its first launch vehicle, the Falcon 1, the development of the Falcon 9 was accelerated by the purchase of several demonstration flights by NASA. This started with seed money from the Commercial Orbital Transportation Services (COTS) program in 2006.[12] SpaceX was selected from more than twenty companies that submitted COTS proposals.[13] Without the NASA money, development would have taken longer, Musk said.[2]

The development costs for Falcon 9 v1.0 were approximately US$300 million, and NASA verified those costs. If some of the Falcon 1 development costs were included, since F1 development did contribute to Falcon 9 to some extent, then the total might be considered as high as US$390 million.[14][2]

In December 2010, the SpaceX production line was manufacturing one new Falcon 9 (and Dragon spacecraft) every three months, with a plan to double the production rate to one every six weeks in 2012.[16]

From early days in the development of the Falcon 9, SpaceX had expressed hopes that both stages would eventually be reusable. The initial SpaceX design for stage reusability included adding lightweight thermal protection system (TPS) capability to the booster stage and utilizing parachute recovery of the separated stage. However, early test results were not successful,[17] leading to abandonment of that approach and the initiation of a new design.

On behalf of Kubernetes SIG Network, we are pleased to announce the v1.0 release of GatewayAPI! This release marks a huge milestone forthis project. Several key APIs are graduating to GA (generally available), whileother significant features have been added to the Experimental channel.

This release includes the graduation ofGateway,GatewayClass, andHTTPRoute to v1, whichmeans they are now generally available (GA). This API version denotes a highlevel of confidence in the API surface and provides guarantees of backwardscompatibility. Note that although, the version of these APIs included in theStandard channel are now considered stable, that does not mean that they arecomplete. These APIs will continue to receive new features via the Experimentalchannel as they meet graduation criteria. For more information on how all ofthis works, refer to the Gateway API VersioningPolicy.

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