MSS: it's a simulation param. Check the "ns3::TcpSocket::SegmentSize" attribute. Default is 536 bytes, but you probably want to enlarge it. See also examples/tcp/tcp-variants-comparison.cc.
RTT: it depends on your simulation. If you don't have huge delays in the routers due to heavy traffic, it can be approximated by knowing the channel delays.
C: it is the channel capacity. You should know it...
Loss: it's the error probability. Again, you should know it.
T.