At Mon, 22 Jun 2015 22:28:06 -0700 (PDT),
you might start with a tutorial to support new application
on top of DCE.
https://www.nsnam.org/docs/dce/manual/html/dce-user-newapps.html
an application is somehow 'directly executed' on a
(simulated) node as if it is running on a usual operating
system. so, the answer to your question would be 'yes'.
see the example of iperf at the document.
-- Hajime