Locus Maps Pro

[Gaby Zenz]

Especially optimized for Locus Map, these OSM based offline vector maps are the best choice for the best price. They contain addresses, points of interest, elevation data, can change themes (hike/bike, winter, road and city) and cover the whole world.

Maps are available in Summer and Winter versions, covering Austria, Germany and Northern Italy. Summer maps display a rich set of topographic features with detailed contour lines, rock drawings, hiking tracks and bike routes. Winter maps are optimized in color and feature ski runs, ski lifts, cross-country skiing tracks and slope gradients.

Detailed and accurate topo and aerial maps of France produced by the largest French cartographic publisher. Topo maps contain complete tourist content including marked hiking and cycling trails. Maps are available online and offline in several zooms down to very detailed 1:10.000.

Maps of Alpine Association of Slovenia display trails, mountain huts, paths, natural and cultural points of interest, tourist infrastructure and everything else important for activities in the nature are represented in detail. PZS maps are continuously updated by volunteers of Slovenian alpine clubs.

Maps of USA based on combination of data from the national parks, national forests, and BLM lands, state parks, local parks, and high-use recreation areas, alongside data from the OpenStreetMap community. An unparalleled mapping product for outdoor recreation and rural use.

IGN Belgium, Onmaps Germany, CUZK Czech rep., Freemap Slovakia, Osmapa Poland, Turistautak Hungary, Cartographia Hungary, USGS USA, Skoterleder Sweden, Statkart Norway, Kapsi Finland, Jana Seta Baltic maps, Topomaps New Zealand, CNIG Spain, Geoscience Australia, Kortforsyningen Denmark, Map5 Netherlands and many others

When I am riding my Bike in the Rain, the Rain Drops Fall on my display and trigger random actions within the locus App (zooming, pausing etc) and minimizing the app itself or changing to another App, closing the app. This is pretty annoying, my Smartphone is water resistant, but during Rain locus Maps is pretty difficult to use (ok, EVERY app is difficult to use ?) especially when navigating and recording is activated, and it should Do nothing Else than this!

I wrote a related topic 6 years ago - -screen-is-not-fully-locked-in-screen-lock-mode-ignore-down-swipe-from-top-of-screen - fortunately my newer phone doesn't not suffer so much from raindrops being interpreted as random taps.

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Lung cancer is a major cause of death in the United States and other countries. The risk of lung cancer is greatly increased by cigarette smoking and by certain occupational exposures, but familial factors also clearly play a major role. To identify susceptibility genes for familial lung cancer, we conducted a genomewide linkage analysis of 52 extended pedigrees ascertained through probands with lung cancer who had several first-degree relatives with the same disease. Multipoint linkage analysis, under a simple autosomal dominant model, of all 52 families with three or more individuals affected by lung, throat, or laryngeal cancer, yielded a maximum heterogeneity LOD score (HLOD) of 2.79 at 155 cM on chromosome 6q (marker D6S2436). A subset of 38 pedigrees with four or more affected individuals yielded a multipoint HLOD of 3.47 at 155 cM. Analysis of a further subset of 23 multigenerational pedigrees with five or more affected individuals yielded a multipoint HLOD score of 4.26 at the same position. The 14 families with only three affected relatives yielded negative LOD scores in this region. A predivided samples test for heterogeneity comparing the LOD scores from the 23 multigenerational families with those from the remaining families was significant (P=.007). The 1-HLOD multipoint support interval from the multigenerational families extends from C6S1848 at 146 cM to 164 cM near D6S1035, overlapping a genomic region that is deleted in sporadic lung cancers as well as numerous other cancer types. Parametric linkage and variance-components analysis that incorporated effects of age and personal smoking also supported linkage in this region, but with somewhat diminished support. These results localize a major susceptibility locus influencing lung cancer risk to 6q23-25.

Loads SQLite-based maps according to actual GPS position. There is no need to select maps manually when out of one, Locus Map switches it on automatically. To make this work, store all the maps in one folder.

You manually select which map to display or you let Locus automatically load available vector maps for the currently displayed position. This also ensures a seamless map display across the whole screen in areas where the coverage of two maps blends into each other.

Displays a line from the user's current position across the screen to indicate the direction he/she is pointing at with the device:
Similar function to the Show view option but more accurate.

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Juvenile hemochromatosis (JH) is a rare autosomal recessive disorder that causes iron overload. In the French Canadian region of Saguenay Lac-Saint-Jean the worldwide largest cohort of JH cases has been identified. Here, we report the mapping of this large cohort of cases to the HFE2 locus on chromosome 1q. A maximum multipoint location score of 7.02 was observed with marker D1S2344. A common ancestral haplotype, showing the presence of a founder effect, was identified. The analysis of recombinants allowed us to confirm the JH candidate region.

Juvenile hemochromatosis, or hemochromatosis type II (JH; MIM 602390), is an inborn error of iron metabolism, which leads to severe iron loading and organ failure at age before 30 years. First symptoms include heart failure, cardiac arrhythmia and hypogonadotropic hypogonadism.1,2,3 JH is a rare disorder, characterized by an autosomal recessive inheritance, distinct from classic-type hemochromatosis or HFE (MIM 235200).4,5

Very recently, two mutations in the antimicrobial peptide Hamp gene, which maps to chromosome 19, have been found in affected members from two JH families. This result increases the genetic heterogeneity of iron-overload diseases and, moreover, identifies a new form of juvenile hemochromatosis.12

A total of 17 JH patients (seven females and 10 males) belonging to 12 families were included in the study (Figure 1). The average age at diagnosis was 24.1 years. The diagnosis was made on the basis of clinical history, physical examination and persistently raised iron indices (% transferrin saturation and serum ferritin). Liver biopsy was performed in at least one affected patient of each sibship. The clinical, biochemical, and genetic characteristics were as previously described.1

Statistical analysis was carried out on the assumption of autosomal recessive disorder with complete penetrance. The disease-gene frequency was set to 0.001, and all marker alleles were considered to be equally frequent. Two-point linkage analyses were performed with ILINK and MLINK programs, version 5.1, from the LINKAGE software package.19,20 The input data files for the multipoint analysis were created using MEGA 2 program.21 The multipoint and haplotype analyses were performed using SIMWALK 2 v.2.82 that calculates the Maximum Location Score (directly comparable with multipoint LOD score) using simulated annealing and MCMC (Monte Carlo Markov Chain) algorithm.22 We assigned a specific allele number for each marker within each family to reduce the time for the analysis.

Unfortunately, no candidate gene is included in the HFE2 region. Nevertheless, 10 genes have been so far selected and analyzed by DHPLC. Negative data have been obtained in all cases. Additional work is now in progress to select more genes using both standard and new approaches, such as microarrays.

In conclusion, the present data demonstrate that the largest worldwide cohort of JH families maps to HFE2. This cohort is the result of a strong founder effect and is useful to further refine the HFE2 candidate region and we confirm the juvenile hemochromatosis locus maps on chromosome 1q.

I'm a longtime GDAK user and like it because as a GSAK (windows) user I can load GDAK with GSAK databases and have (log) images included for offline use as well as offline maps. I cache with an Oregon 600 and have GDAK for map overviews and on holiday I use GDAK to refresh cache data and log via API without using the website.

I've also heard good things about Geooh Live. I've heard that Locus is a good navigation app, and that the Geocaching plugin allows its use for geocaching. I've heard that GDAK is like GSAK, but since I don't use GSAK, that isn't really a selling point for me.

Entering coords manually into Locus? Definitely, in your choice of coordinate formats. But it'll also fetch PQs directly from Groundspeak, so it's likely rare you'll have to enter any manually. It can also work online, but really excels at offline caching, the way GPS units work.

As a map app, it's feature-rich like you wouldn't believe. I'm still discovering features after 3-4 years of using it. As a caching app, it has way more than I personally need, leaving out only "edge case" stuff like souvenirs, message center, and geotours.

PPS, on re-reading your post... If you're in the field with your pre-loaded PQs, in Locus, you'll see 5 logs per cache. If you need more logs than that and have cell signal, there's a "download logs" feature that loads many more, up to 90 I think. You can also "offlinize", which means pre-loading images (spoilers etc.) before leaving WiFi/cell range.

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