That suggests a syntax error in your setting file. Double check any changes you've made for missing commas and things like that. Are you using the variable 'settings' in there at all (as hinted by the error message)?
If you can't track it down, no need to reinstall. Backup you current settings file then delete it. Run Node-RED - it should copy a default settings file back in place. You can then progressively add back your particular settings.
Nick
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