Always follow your funding opportunity's instructions for application format. Although these applications demonstrate good grantsmanship, time has passed since these grant recipients applied. The samples may not reflect the latest format or rules. NIAID posts new samples periodically.
The text of these applications is copyrighted. Awardees provided express permission for NIAID to post these grant applications and summary statements for educational purposes. Awardees allow you to use the material (e.g., data, writing, graphics) they shared in these applications for nonprofit educational purposes only, provided the material remains unchanged and the principal investigators, awardee organizations, and NIH NIAID are credited.
Freedom of Information Act (FOIA). NIAID is strongly committed to protecting the integrity and confidentiality of the peer review process. When NIH responds to FOIA requests for grant applications and summary statements, the material will be subject to FOIA exemptions and include substantial redactions. NIH must protect all confidential commercial or financial information, reviewer comments and deliberations, and personal privacy information.
Note on Section 508 Conformance and Accessibility. We have reformatted these samples to improve accessibility for people with disabilities and users of assistive technology. If you have trouble accessing the content, please contact the NIAID Office of Knowledge and Educational Resources at dea...@niaid.nih.gov.
The Research Enhancement Award (R15) program supports small-scale research projects to expose students to research and strengthen the research environment at educational institutions that have not been major recipients of NIH support. They are awarded for up to 3 years.
The R21/R33 supports a two-phased award without a break in funding. It begins with the R21 phase for milestone-driven exploratory or feasibility studies with a possible transition to the R33 phase for expanded development. Transition to the second phase depends on several factors, including the achievement of negotiated milestones.
The SBIR (R43/R44) and STTR (R41/R42) programs support domestic small businesses to engage in research and development with the potential for commercialization. Read more about NIAID Small Business Programs.
*Dr. Mark Poritz submitted the original grant application. In the course of the first year of funding, Dr. Andrew Hemmert took on increasing responsibility for the work. For the grant renewal, Dr. Poritz proposed that Dr. Hemmert replace him as the PI.
The Research Scientist Development Award (K01) supports those with a research or health-professional doctoral degree and research development plans in epidemiology, computational modeling, or outcomes research. Read more about NIAID Research Career Development (K) Awards.
The Mentored Clinical Scientist Research Career Development Award (K08) supports those with current work in biomedical or behavioral research, including translational research, a clinical doctoral degree such as M.D., D.V.M., or O.D., and a professional license to practice in the United States. Read more about NIAID Research Career Development (K) Awards.
The Mentored Patient-Oriented Research Career Development Award (K23) supports those with a clinical doctoral degree, who have the potential to develop into productive, clinical investigators, and who have made a commitment to focus their research endeavors on patient-oriented research. Read more about NIAID Research Career Development (K) Awards.
The Extramural Associate Research Development Award (EARDA) (G11) provides funds to institutions eligible to participate in the NIH Extramural Associates Program for establishing or enhancing an office of sponsored research and for other research infrastructure needs. Search for NIAID G11 Opportunities.
The U01 research project cooperative agreement supports a discrete, specified, circumscribed project for investigators to perform in their areas of specific interest and competency. Learn more about NIAID Cooperative Agreements (U).
You'll find several kinds of fields in your application forms - check boxes, dates, data entry fields, and attachments. This page provides guidance on attachments. Attachments are documents that are prepared outside the application using whatever editing software you desire (e.g., Microsoft Word), converted to PDF format, and then added or uploaded to your application. We require PDF format to preserve document formatting and a consistent reading experience for reviewers and staff.
We have very specific attachment formatting requirements. Failure to follow these requirements may lead to application errors upon submission or withdrawal of your application from funding consideration.
Adherence to font size, type density, line spacing, and text color requirements is necessary to ensure readability and fairness. Although font requirements apply to all attachments, they are most important and most heavily scrutinized in attachments with page limits.
The following guidance may assist you in developing a strong application that allows reviewers to better evaluate the science and merit of your proposal. This page provides tips for demonstrating to reviewers and NIH staff the high quality of the personnel involved in your project and documenting resources and institutional support of the project. We provide information for new investigators and foreign applicants, as well.
Though the advice provided is relevant for all research grants, it is general in nature and geared toward the NIH Research Project (R01). The tips should not replace your organization's internal guidance, specific advice provided by NIH program or grants management staff, or instructions found in the funding opportunity or application guide.
If instructions in the application guide and funding opportunity conflict, the opportunity wins. If instructions in either the application guide or funding opportunity conflict with an NIH Guide notice (including a Notice of Special Interest), the notice wins.
Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria, and additional review criteria (as applicable for the project proposed).
Reviewers will consider each of the review criteria below in the determination of scientific and technical merit, and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field.
Note that an application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field.
As applicable for the project proposed, reviewers will evaluate the following additional items while determining scientific and technical merit and in providing an overall impact score, but will not give separate scores for these items.
As applicable for the project proposed, reviewers will consider each of the following items, but will not give scores for these items and should not consider them in providing an overall impact score.
Sufficient information must be included to demonstrate to reviewers and NIH staff the high quality of the PD/PI, the co-investigators, available research resources, and the applicant institution and its support of the project.
Applicants should clearly state that they have the appropriate resources to conduct the research, such as adequate equipment and laboratory space. When possible, include letters of commitment for these resources.
Determine the expertise needed for your research study team (individuals, collaborating organizations, resources, etc.). Most scientific work requires collaboration among researchers, and NIH is dedicated to fostering such relationships.
Although optional in most cases, the Cover Letter attachment on the SF424 (R&R) form and the PHS Assignment Request Form can be used to convey information to the Division of Receipt and Referral (DRR) in the Center for Scientific Review.
The research plan describes the proposed research, stating its significance and how it will be conducted. Remember, your application has two audiences: the majority of reviewers who will probably not be familiar with your techniques or field and a smaller number who will be familiar.
The following elements need to be included in the grant application as appropriate. Unless stated, these elements do not influence the rating (priority score) of the application. However, the reviewers are asked to comment on the adequacy of the information provided for each element. Any concerns the reviewers identify may negatively affect and postpone the granting of an award.
Note: Upon submission, NIH Systems will automatically add: headers, footers (time stamping, tracking number, funding opportunity number, and page numbers). Therefore, do not include headers or footers.
I need to use one rather poorly-coded application which requires me to use en-US regional settings, or more specifically, the date format needs to be in en-US format when executing that application. I don't want to use en-US date format when I regularly use my PC. I'd like to start this application using just a double-click, without changing the regional settings manually when using it.
I have created a special user as a member of "Administrators" group (this program requires elevation) and set its regional settings to en-US, with the idea to use runas to launch this application using the different user credentials, hoping that if I launched the app this way, it would pick up the given user regional setting.
I have been able to solve this particular problem using a simple, quick and dirty way. As all this application requires is changing the date format (more specifically, short date format) I have created an application which:
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