I think that the system call to unzip is the safest mechanism. It would be lossless. Convering with MRIConvert, or any of the other possible tools will only convert the parts of the nii.gz file that are known to that particular tool.
In particular, proprietary nifti extensions would be last.
With that stated, it “probably” does not affect you since your nifti files are “probably” simple and the conversions would be fine.
Hans
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