Erythorbicacid (isoascorbic acid, D-araboascorbic acid) is a stereoisomer of ascorbic acid (vitamin C).[1] It is synthesized by a reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose or by strains of Penicillium that have been selected for this feature.[2] It is denoted by E number E315, and is widely used as an antioxidant in processed foods.[3]
Clinical trials have been conducted to investigate aspects of the nutritional value of erythorbic acid. One such trial investigated the effects of erythorbic acid on vitamin C metabolism in young women; no effect on vitamin C uptake or clearance from the body was found.[4] A later study found that erythorbic acid is a potent enhancer of nonheme-iron absorption.[5]
Since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods intended to be eaten fresh (such as salad bar ingredients), the use of erythorbic acid as a food preservative has increased.
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In a survey of double-bind design, 3 groups of approximately 70 student volunteers took 1 g L-ascorbic acid, 1 g D-isoascorbic acid, or placebo tablets every day for 15 weeks and the incidence and duration of colds were recorded. The group taking D-isoascrobic acid suffered 34% fewer colds than the other two groups; the results were also analyzed in relation to the sex and smoking habits of the volunteers. The rationale for investigating D-isoascorbic acid, an isomer of L-ascorbic acid which has limited antiscorbutic activity, is discussed.
Erythorbic acid or erythorbate, formerly known as iso ascorbic acid and D-arabo ascorbic acid, is a stereoisomer of ascorbic acid.And its chemical properties have many similarities with Vc, but as an antioxidant, it has the inimitable advantage that Vc do not have: First, it is superior to the anti-oxidation than Vc
And its chemical properties have many similarities with Vc, but as an antioxidant, it has the inimitable advantage that Vc do not have: First, it is superior to the anti-oxidation than Vc, therefore, mixed the Vc, it can effectively protect the properties Vc component in improving the properties have very good results, while protecting the Vc color. Second, higher security, no residue in the human body, participating in metabolism after absorb by human body, which can be transformed into Vc partially. In recent years, Chinese medicine take it as complementary information be used in Vc film, Vc Yinqiao-Vc and health care products, and obtain good effect. Specification: 99%min Other name: D-erythro-Hexonicacid, 3-keto-, g-lactone(6CI);Erythorbic acid (7CI);Araboascorbic acid; Araboascorbic acid, D-;D-(-)-Isoascorbic acid;D-Araboascorbic acid;D-Erythorbic acid;D-Isoascorbicacid;D-arabino-Ascorbic acid;Glucosaccharonic acid;Isoascorbic acid;Isovitamin C;Saccharosonic acid
1.Erythorbic acid is produced in acidic condition by sodium erythorbate.
2.Erythorbic acid has strong reducing action and has effects on reducing blood press, diuresis,generationg liver glycogen,excreting pigment,detoxifying the body.
3.It is non-toxic.Its other applications are familiar to sodium erythorbate. Sodium erythorbateand erythorbic acid are generally recognized as the lastest A-class Green products internationally and have become the commodities in short supply both at home and abroad
In this study, high performance liquid chromatography (HPLC) was used to analysis the content of citric acid and D-isoascorbic acid in beverages. The samples were separated by C18 chromatography column, 0.1 % phosphoric acid solution was used as the mobile phase with the flow rate of 0.5 mL/min, the column temperature was 35 C, and the detection wavelength was 210 nm. The results showed that the content of citric acid and D-isoascorbic acid has a good linear correlation (r>0.99) within the range of 50 μg to 200 μg. The selectivity, recovery and precision of citric acid and D-isoascorbic acid were suitable. Meanwhile, this method could be used to detect the content of citric acid and D-isoascorbic acid in beverages.
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Introduction (D-isoascorbic acid CAS No. 89-65-6)
D-isoascorbic acid is a natural, green and highly effective food antioxidant, which plays a considerable role in improving the stability of food and extending the storage period. As an isomer of Vc, D-isoascorbic acid has many similarities in chemical properties with Vc, but as an antioxidant, it has advantages that Vc does not possess. First of all, its oxidation resistance is better than that of Vc. Therefore, when used with VcChemicalbook, it can effectively protect the medicinal components of Vc, and has a good effect in improving the medicinal properties, while protecting the color of Vc. Second, the safety is high, there is no residue in the human body, and the body participates in metabolism after ingestion, which can be partially converted into Vc. In recent years, it has been applied to Vc tablets, Vc Yinqiao tablets and Vc health products as a kind of auxiliary materials for medicine, and has achieved good results.
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The ability to identify L(+)-ascorbic acid from D(-)-isoascorbic acid in medicinal products is of practical interest. Based on the method of frequency domain weak measurement, a set of common optical path sensors for identification of L(+)-ascorbic acid and D(-)-isoascorbic acid is established. By quantificationally analyzing the magnitude and offset direction of the spectral central wavelength, a good identification of the concentration and the optically active forms of ascorbic acid has been achieved. The sensitivity and resolution of the sensor for optical rotation can reach 34.35 nm/ and $5.53 \times 10^ - 5^\circ $, respectively. The detection resolution for L(+)-ascorbic acid is $2.00 \times 10^ - 4\;\rm mol/\rm mL$, and that for D(-)-isoascorbic acid is $2.73 \times 10^ - 4\;\rm mol/\rm mL$. The potential of the sensor in the detection of transparent but optically inactive impurities has been verified by comparative experiments of sodium chloride solution. The sensor also has been applied to identify medicinal vitamin C tablets, which verified the feasibility of the method in optically active pharmaceutical solutions with water-insoluble, optically inactive impurities. Since the sensor has the advantages of high precision, real-time, high robustness, and being non-destructive, it has a great prospect in the field of drug detection containing chiral molecules.
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D-sorbitol is a sugar alcohol naturally found in many fruits. L-ascorbicacid is a compound that can be synthesized by plants and some animals but mustbe externally taken by humans because it cannot be synthesized due to the lackof L-gulono-γ-lactone oxidase enzyme. D-sorbitol and L-ascorbic acid are twoingredients that are frequently used in the food, chemical, pharmaceutical andcosmetic industries and may have a number of positive effects on human health.These ingredients are generally produced commercially from D-glucose by aseries of chemical and biochemical reactions. In the commercial production ofthese compounds, Reichstein-Grssner or two-stepfermentation methods are generally used. In this study; the properties, fieldsof usage, effects on human health and production methods of D-sorbitol andL-ascorbic acid are reviewed.
D-sorbitol birok meyvede doğal olarakbulunan bir şeker alkoldr. L-askorbik asit ise bitkiler ve bazı hayvanlartarafından sentezlenebilen ancak insanlar tarafından L-gulono-γ-lakton oksidazenzimi eksikliği nedeniyle sentezlenemediği iin dışarıdan alınması zorunluolan bir bileşiktir. D-sorbitol ve L-askorbik asit gıda, kimya, ila vekozmetik sektrlerinde sıklıkla kullanılan ve insan sağlığı zerine birokolumlu etkileri bulunan iki rndr. Bu rnler D-glikozdan kimyasal vebiyokimyasal reaksiyonlar ile ticari olarak retilmektedirler. Bu bileşiklerinticari retiminde genellikle Reichstein-Grssner veya iki aşamalı fermantasyonyntemleri kullanılmaktadır. Bu alışmada D-sorbitol ve L-askorbik asidin bazızellikleri, kullanım alanları, sağlık zerine etkileri ve retim yntemleriderlenmiştir.
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