Fw: Higher colistin doses do not improve mortality

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ogah okechukwu

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Oct 16, 2016, 1:23:46 PM10/16/16
to Nigerian Cardiac Society
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Dr O.S Ogah. MBBS, MSc, FWACP, FACP, FESC, FACC, FCAI
Consultant Physician/ Cardiologist,
Division of Cardiology
Department of Medicine,
University College Hospital Ibadan
PMB 5116, Ibadan , Oyo State , NIGERIA
Tel. +234 806 47 77 211
Fax (Electronic). +1215-975-6817
 


On Saturday, October 15, 2016 10:38 PM, Healio/Infectious Disease News <IDN-Sy...@SLACKINC.COM> wrote:


Also: MRSA unlikely to be eradicated from nursing homes
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Higher colistin doses do not improve mortality rates
Benattar YD, et al. Clin Infect Dis. 2016;doi:10.1093/cid/ciw684.
Higher doses of colistin did not reduce 28-day mortality rates compared with lower doses administered to patients with infections caused by carbapenem-resistant gram-negative bacteria, according to recent findings. Researchers, however, found that higher colistin dosing was associated with an increased risk for nephrotoxicity.
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Biologics associated with increased risk for herpes zoster in immunocompromised patients
Marra F, et al. Open Forum Infect Dis. 2016;doi:10.1093/ofid/ofw205.
Patients who took biologics to treat autoimmune diseases showed an increased risk for herpes zoster infection, according to data from a meta-analysis.
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Erik Dubberke
Hospital food unlikely source for C. difficile acquisition
Dubberke ER, et al. Infect Control Hosp Epidemiol. 2016;doi:10.1017/ice.2016.218.
Hospital food was unlikely to be a source of Clostridium difficile acquisition at Barnes-Jewish Hospital in St. Louis, according to Erik R. Dubberke, MD, MSPH, and colleagues.
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MRSA likely to persist in nursing homes; large-scale outbreaks doubtful
Batina NG, et al. Antimicrob Resist Infect Control. 2016;doi:10.1186/s13756-016-0130-7.
Mathematical models describing the transmission dynamics of MRSA in nursing home settings showed that MRSA is unlikely to be eradicated from the facilities, but large-scale outbreaks also are unlikely.
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Suboptimal ART adherence associated with inflammation despite viral suppression
Castillo-Mancilla JR, et al. Clin Infect Dis. 2016;doi:10.1093/cid/ciw650.
Suboptimal adherence to ART was associated with higher levels of inflammation and immune activation in patients with HIV even if the virus was suppressed, according to an analysis of data from the Multicenter AIDS Cohort Study.
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