Arbor protruding problem in direct current stimulation to cortical surface

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yamazaki

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Jun 11, 2024, 6:36:16 AM6/11/24
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Hello everyone,

I am currently working on simulating direct current stimulation from cortical surface using S1 simulation model in the paper mentioned in https://www.frontiersin.org/articles/10.3389/fninf.2022.884245/full(https://www.frontiersin.org/articles/10.3389/fninf.2022.884245/full)
I want to simulate direct current stimulation to cortical surface.
Now , I use simulated electrode for electrical stimulation, which is placed on the surface of S1.

In this simulation model, some of distances from soma to the shallowest arbor of the cell are longer than the shallowest points of each layer. For instance, the distance from  the shallowest arbor of L5_TTPC2_cADpyr232_1 to soma is 1212 µm, while the L5 range is 858~1382 µm(i.e.,858 µm < 1212 µm). In this situation, if the simulator places a soma of  L5_TTPC2_cADpyr232_1 at 1000 µm from the surface of S1, 212 µm of arbor are protruding.

Does anyone have any suggestions to address this issue?

Thank you in advance.

Best regards, yamazaki.

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