I don't know what you mean by that. To change permissions, you just go to the Netbox's Admin > Admin link, and then edit Users or Groups as appropriate. There's no need to redeploy anything.
The only thing you'd need to redeploy for is changing the settings in configuration.py, but there's nothing that you'd change there except REMOTE_AUTH_DEFAULT_GROUPS, and that one only affects new users who connect for the first time. Typically you'd have a group called "default" or "read_only" or something like that, which all the lowest-level users get, and you'd stick with this choice forever. You can of course change the permissions assigned to this group without redeploying.