I just rotated the 15 tubes in my big clock after 11 months. They display the same numeral 24/7, which I believe is the worst-case scenario for cathode poisoning.
12 tubes showed no signs of degradation
3 tubes showed slight degradation:
- A slightly dim tube is now fine after running 12 hours at nominal current
- A slightly dimmer tube is better after 12 hours at nominal current, but not quite healed. Perhaps it will take a few days
- Lastly, a '2' was not illuminating at the center. After 12 hours, it's fully illuminated, though slightly dimmer
I did not check all digits for each tube; I simply rotated them to their next position. So it is possible that other digits are damaged. After the above 3 tubes have settled-in, I will do a thorough check of all cathodes.
Conclusion ? Cathode poisoning definitely happens, though it seems to take quite awhile. It also appears to be reversible as long as it was not severe. I'll post an update in a few weeks when I do thorough testing.