Sage Act Pro 2013 Keygen
Gro Bert
Please donate today by visiting -renderer-app.donorperfect.io/give/sage-eldercare/annual. If you would like to give a donation in the form of a qualified charitable donation from your IRA, a grant from a Donor Advised Fund, a gift of appreciated securities or a legacy in your estate plan, please give us a call at 908-598-5504 for assistance. If your employer offers company matching, please submit your request and provide their name to us for our records. For a list of companies offering matching contributions click here.
Sage tea has been traditionally used for the treatment of digestive and circulation disturbances, bronchitis, cough, asthma, angina, mouth and throat inflammations, depression, excessive sweating, skin diseases, and many other diseases.[5,6,7] Salvia essential oils have been used in the treatment of a wide range of diseases like those of the nervous system, heart and blood circulation, respiratory system, digestive system, and metabolic and endocrine diseases. In addition, sage essential oil has been shown to have carminative, antispasmodic, antiseptic, and astringent properties.[8,9]
The essential oil of Salvia species has various compositions depending on the genetic, climatic, seasonal, and environmental factors.[10] Some chemical compounds like flavonoids, terpenoids, and essential oils are present in different species of Salvia [Figure 4].[3] Essential oils are very important sources for the screening of anticancer, antimicrobial, antioxidant, and free radical scavenging agents.[11] S. officinalis (common sage) is considered to have the highest amount of essential oil compared to the other species of Salvia.[5,12]
In all analyzed samples of S. officinalis, the major components, although present in different concentrations, are: 1,8-cineole, camphor, borneol, bornyl acetate, camphene, α- and β-thujone, linalool, α- and β-caryophyllene, α-humulene, α- and β-pinene, viridiflorol, pimaradiene, salvianolic acid, rosmarinic acid, carnosolic acid, ursolic acid, etc.[7,12] Studies have shown that some biological properties of the essential oil of Salvia depend on camphor, 1,8-cineole, α-thujone, and β-thujone.[9] The essential oil of sage contains about 20% camphor, and as the leaves expand, the camphor content also increases.[13] In a study, the most powerful scavenging compounds were reported to be α-thujone and β-thujone, bornyl acetate, camphor, menthone, and 1,8-cineol in the essential oil.[11] In the same study, the essential oil of Melissa officinalis and S. officinalis showed better antioxidant activities than some other Lamiaceae plants.[11]
In a study conducted on the antioxidant activity of many plant extracts, like sage (S. officinalis), it was found that the phenolic and flavonoid compounds are mainly responsible for the antioxidant and free radical scavenging effects of these plants.[18,19] Phenolic compounds such as carnosol, carnosic and rosmarinic acids, rosmadial, rosmanol, epirosmanol, methyl carnosate, and luteolin-7-O-β-glucopyranoside have a high antioxidative activity and are usually extracted from sage with ethanol.[20] The phenolic compounds can either stimulate endogenous antioxidant defense systems or scavenge reactive species.[21]
A study shows that S. officinalis improves the memory and cognition, and with increasing dosage, the mood gets elevated as well as alertness, calmness, and contentedness increase.[29] A randomized, double-blind clinical study has shown that an ethanolic extract from common sage (S. officinalis) as well as Spanish sage (S. lavandulaefolia) is effective in the management of mild to moderate AD, and study on patients did not show any adverse effect on them on taking sage.[30,31] Administration of S. lavandulaefolia (Spanish sage) has been reported to be effective in improving the speed of memory and mood. Salvia essential oil also has been reported to improve immediate word recall.[27]
A number of studies have investigated the effects of the aromas of plant essential oils on cognition and mood.[32] The aroma of S. officinalis produced significant enhancement effect in the quality of memory factor derived from Cognitive Drug Research (CDR) system.[32] The findings suggest that the aromas of essential oils of Salvia species have some, but not all the effects found following the oral consumption of the herb.[32] The antioxidant and anti-inflammatory properties of the S. officinalis or S. lavandulaefolia may offer a long-term protection in the pathogenesis of dementia.[29] Also, the mood-enhancing properties of the herb may have applications in the treatment of advanced dementia, in which disturbed mood and agitation feature as a major problem.[29] There is no report of negative side effects associated with S. officinalis or S. lavandulaefolia despite many years of usage.[29]
Colorectal cancer (CRC) is a common type of cancer and a significant cause of mortality in Western societies. It develops by genetic and epigenetic alterations which transfer normal colon cells to proliferating cells.[38] This study has shown that dietary compounds can change the epigenetic status. Many food plants are rich in bioactive compounds and have shown to possess anticancer properties.[38] The effect of drinking sage (S. officinalis) herbal tea was studied on the prevention of colon cancer in rats. It was found that S. officinalis water extract significantly decreased the oxidative H2O2-induced DNA damage in vitro.[38]
A study showed that sage, along with different plant extracts was comparable to synthetic preservatives, and the result confirmed that the aqueous extract of S. officinalis can be used in biotechnology as a natural preservative ingredient in food industry.[24]
The majority of antioxidant effects are attributed to Salvia phenolic compounds such as rosmarinic acid, salvianolic acid, sagecoumarin and sagerinic acid as they exhibit strong radical scavenging activity with approximately 90% of 2,2-diphenylpicrylhydrazyl (DPPH) scavenged under the experimental conditions. In fact, their effects were substantially greater than the sage flavonoids, luteolin and apigenin [48]. In another in vitro study, salvianolic acid L showed potent free radical scavenging activities for DPPH and superoxide anion radicals. It was identified as a significantly better scavenger of these free radicals than trolox (a water-soluble analogue of vitamin E), caffeic acid and rosmarinic acid [49].
The cognitive-enhancing effects of acute, single administration of different Salvia species has been investigated in six studies, five utilising randomised, double-blind, placebo-controlled designs. In five studies, the efficacy of Salvia plants in healthy young adults was investigated, while one was conducted on healthy, older-age volunteers. Positive cognitive (e.g. secondary memory, attention, word recall and speed of memory) and mood-enhancing (e.g. alertness, calmness and contentedness) effects from the single administration of differing dosages of essential oil of S. lavandulaefolia in healthy adults was demonstrated [22, 81, 82]. Improvements in mood (e.g. alertness, contentedness, and calmness) and cognition were also identified following the single administration of a S. officinalis extract to healthy young adults [18], and enhancement in memory and attention were revealed following the single administration of S. officinalis to healthy, older-age adults [19]. In a randomised, single-blinded design (participant-masked), Moss et al. [83] also found positive cognitive and mood-enhancing effects from acute exposure to the aroma of S. officinalis and S. lavandulaefolia.
The greater sage-grouse is a large grouse with a chunky, round body, small head and long tail. Males change shape dramatically when they display, becoming an almost spherical shape, as they puff up their chest, droop their wings and fan their tail into a starburst.
The greater sage-grouse breeds in western United States, with their range covering portions of Oregon, California, Nevada, Idaho, Utah, Colorado, Wyoming and Montana. They may be residents throughout the year or migrate seasonally. Movements vary dramatically because of differences associated with several factors, including seasonal habitat quality and weather.
In order to access certain Services offered through the Site, you may be required to pay fees and/or accept additional terms and conditions and in such event you may be provided with a number, code or other sequence that provides access to certain restricted Services (the \"ID\" ) and to your account (the\"Password\" ). You are the sole and exclusive owner of the Password and ID combination. Maintaining the confidentiality and security of your Password and ID is solely your responsibility. You are fully responsible for the use and protection of the Password and ID and for all transactions undertaken by means of any account opened, held, accessed or used via your Password and ID. You shall notify us immediately and confirm in writing any unauthorized use of accounts or any breach of security, including, without limitation any loss, theft or unauthorized use of your Password(s), IDs and/or account number(s). If we have reasonable grounds to suspect that the security of your Password has been compromised, we have the right to suspend or terminate your account, refuse any and all current or future use of the Services, and pursue any appropriate legal remedies. We shall not be responsible for any losses incurred in connection with any misuse of any Password or ID. You shall notify SAGE by emailat onlines...@sagepub.com of any known or suspected unauthorized use of the Services, of any known or suspected breach of security, including, without limitation, loss, theft, or unauthorized use of your Password or ID.
If you have any comments, questions or concerns about anything you have read on this page or you are concerned how your personal information has been handled by SAGE, you can contact our Information Privacy Officer at data.pr...@sagepub.com or for marketing specific queries please see marketing preferences section above.
aa06259810