I have exactly the same question, also for a large project. I look
forward to the response.
On a separate note, Rana, when you begin developing with the Portable
Areas you'll find that js and css development is slowed down
considerably by the need to recompile at each iteration (since the
content files are all compiled as embedded resources). The following
post discusses a few settings changes to IIS - namely adding a virtual
directory for the portable area - that allows you to avoid this and to
continue working directly with the file system files.
http://groups.google.com/group/mvccontrib-discuss/browse_thread/thread/966a12e7009b310e