Quality metrics from DIANN output for MSstats+

[Luca De Corso]

Hello MSstats team, 

I am currently using MSstats+ on data processed with the latest version of DIA-NN. I'm wondering if you have any suggestions on which quality metric variables from the DIA-NN output could be useful to include in the anomaly score calculation.

Thanks in advance,

Luca

[Anthony Wu]

Hi Luca,

We've been using "Ms1ProfileCorr", "Evidence", and the delta retention time, which can be computed by computing the difference between the two columns:  RT - PredictedRT.   We've observed these metrics don't correlate too much with each other.

Thanks,

Tony

[Luca De Corso]

Thanks a lot, I'll try.