about opening a new window or tab

[ginzzer]

Hi there,
I am looking for a way to open a special links in the (same) window
with specific title. For example, I try to open any links from site A in
a window titled DEST. If I keep the window DEST opened, with the
javascript window.open( _url, "DEST"), all links will be opened in the
same window (DEST). However, if I close the window site A and open it
again, even the window (DEST) is still there, since the relation between
the parent and child window changed, so the link from site A will be
opened in a new window. That's way I fail to do that with greasemonkey.
I am new to extension development, before I start, I want to ask if it
is possible to force all links from site A opened in the same window
(even when we close site A and open again) ?