Conditions for performing division
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Эрвин Визард
Oct 22, 2021, 6:40:01 PM10/22/21
to Morpheus users
Dear colleagues, sorry for the naive question, but I need clarification.
How to set a condition on the number of a certain type's cells in Morpheus, above which their division, for example, can not be executed?
How to set a condition on the number of a certain type's cells in Morpheus, above which their division, for example, can not be executed?
Эрвин Визард
Oct 23, 2021, 3:07:40 PM10/23/21
to Morpheus users
Maybe someone knows how to limit division basing on current time and time limit?
суббота, 23 октября 2021 г. в 01:40:01 UTC+3, Эрвин Визард:
Jörn Starruss
Oct 25, 2021, 12:38:54 AM10/25/21
to morpheu...@googlegroups.com
Dear Erwin,
The cell division component tests the given condition every MCS, i.e. CPM step.
Assuming a cell type named 'epithel' was created, Morpheus provides the symbol celltype.epithel.size that represents the current population size. Thus,
<Condition> p_division * (celltype.epithel.size
< 100) </Condition>
would allow divisions with probability p_division until a population size 100 is reached.
Best regards,
Jörn Starruß
Am 23.10.21 um 00:40 schrieb Эрвин
Визард:
Dear colleagues, sorry for the naive question, but I need clarification.
How to set a condition on the number of a certain type's cells in Morpheus, above which their division, for example, can not be executed?
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Эрвин Визард
Oct 25, 2021, 2:12:55 AM10/25/21
to Morpheus users
Dear Jörn,
Thank you very much for your answer! I will check it.
And for any time limit I used such condition which combine probability of division and time step function:
Thank you very much for your answer! I will check it.
And for any time limit I used such condition which combine probability of division and time step function:
rand_uni(0,1) < 10e-3 / celltype.ct2.size * ( 1 - (time^10)/(2400^10 + time^10) )
But time step function based on Hill equation with high n. And it can be not the computationally economic way.
понедельник, 25 октября 2021 г. в 07:38:54 UTC+3, Jörn Starruss:
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