ICM Commands for Molecular and Solvent Accessible Surfaces

[Andrew Orry]

Q: What does the "Receptor Pocket" visualization in ICM represent? Is it solvent accessible surface area or molecular surface area, and can it be changed?
A: The "Receptor Pocket" visualization corresponds to the molecular surface (also called the skin surface). This is the same as running the command: make grob skin

This is also the surface generated in the GUI when you right-click on a ligand and select:
Pocket → Receptor Pocket

To visualize the solvent accessible surface area, use the command: make grob surface

For more details, see:

https://www.molsoft.com/icm/icm-commands.html#make-grob-skin