Molecular networking with data data acquired simultaneously in postive and negative modes

[Vinícius Galvão Wakui]

Hi everyone,

I´m working with a data acquired simultaneously in postive and negative modes, and I notice that GNPS has annotated only precursor ions in positive ion mode. I didn´t found any annotation for data in negative ion mode. My doubt is: is possible to do a molecular networking with a data acquired simultaneously in negative and positive ion mode? Actually it´s the first time I received a data in this conditions, I used to work with data acquired in negative and positive ion mode separately, I mean different files for which analysis.

[Mingxun Wang]

Yes, reach out to my lab, we have tools for this if you'd like to work together can connect you with my phd student putting this out.