Sent: 5/4/2008 11:52:04 A.M. Central Daylight Time
Subj: MELATONIN - breast cancer, leukemia and neurodegenerative
SUBJECT: MELATONIN - BREAST CANCER, LEUKEMIA AND
David E. Blask, Ph.D., M.D.
The Research Institute
One Atwell Road
Cooperstown, NY 13326 [ http://www.bassett.org/institute.cfm
Dear Dr. Blask: I have copied below an article quoting you re
the importance of melatonin primarily re breast cancer growth and the
significance of sleep.
In addition to your extremely important comments re how melatonin
actually slows breast cancer growth, you echo recommendations by Dr.
Russel Reiter, University of Texas/San Antonio of a decade ago in his
book titled "Melatonion." You state "sleepiness" may be the
nastiest side effect." In Dr. Reiter's book, he does include some
instances that may require special consideration re melatonin
consumption but his overall opinion was and still is that melatonin is
essential to good health in countless ways. Information since
publication may now offer insight into even those relatively few
Dr. Reiter, told me (September 2004), in person, that if my
husband had been taking melatonin all along, he may never have
developed Alzheimers. At the time, I was reporting improvement in
three parts of my husband, Bud's Executive Function and that his
neurologist (a leading practitioner here in Minneapolis, Minnesota)
stated, "he does not have Alzheimers." Prior to taking nightly
melatonin and moving his electric clock radio off his nightstand --
close, chronic, prolonged electric field "nightly exposure" is known
to reduce the pineal gland's ability to produce melatonin -- Bud had
many years of declining neuropsych tests. A PET Scan, along with
improved test results as well as my personal observation,
documentation and reports re improvement in memory and cognitive
function, resulted in reversal of diagnosis of Alzheimers. I now
refer to Bud's ongoing memory problems and cognitive dysfunction as
"Reactive Dementia." While I had not yet started applying the term
"Reactive Dementia" at the time of my appeal to Dr. Marilyn Albert,
Alzheimers' Advisory Board Task Force, important background
information re other EMF/EMR exposures in our family, as well as our
melatonin usage is contained in my letter to Dr. Albert at the
The WebMD article quoting you is immediately below. I will also
include a link to a recent study by Dr. Russel Reiter that refers to
possibly delaying Alzheimers and Parkinsons and/or reducing the
severfity of neurodegenerative diseases.
* * *
WebMD - BREAST CANCER HEALTH CENTER
Hormone Melatonin Slows Breast Cancer
Bright Light at Night Linked to Increased Cancer Risk
By Daniel J. DeNoon
WebMD Medical News
July 14, 2003 (Washington, D.C.) -- The nighttime hormone
melatonin puts breast cancer cells to sleep. It also slows breast
cancer growth by 70%.
David E. Blask, MD, PhD, of Bassett Research Institute in
Cooperstown, N.Y., reported the findings at this week's annual meeting
of the American Association for Cancer Research.
Breast cancers get revved up by a kind of dietary fat called
linoleic acid. Melatonin interacts with linoleic acid, so he gave
melatonin to mice implanted with human breast cancers.
"This breast cancer rev-up mechanism gets revved down by
melatonin," Blask said at a news conference. "Nighttime melatonin is a
relevant anticancer signal to human breast cancers. Ninety percent of
human breast cancers have specific receptors for this signal."
The hormone seeps from a pea-sized gland in the brain when the
lights go out at night. It's the reason you get sleepy when it's dark.
Blask and colleagues found that melatonin puts cancer cells to sleep,
Blask's team exposed lab mice with human breast cancers to
constant light. Tumor growth skyrocketed.
"With constant light, tumors grow seven times faster and soak up
incredible amounts of linoleic acid," he says. "During the day, the
cancer cells are awake and linoleic acid stimulates their growth. But
at night cancer cells go to sleep. When we turn on lights at night for
a long time, we suppress melatonin and revert back to the daytime
The finding may explain why nurses who often work the night shift
have high rates of breast and colon cancer.
Blask says clinical trials are under way to see whether melatonin
supplements can help treat cancer. It may also help in other ways.
"When you take melatonin prior to normal onset of sleep, it will
[jump-start the sleep cycle]," he notes. "Many cancer patients suffer
from sleep problems. Melatonin may also improve the quality of life in
cancer patients by helping them sleep."
Arizona Cancer Center researcher David Alberts, MD, notes that
there is a lot of interest in melatonin as a sleep inducer. However,
he worries about the safety of over-the-counter melatonin supplements.
"The issue is safe dosing of melatonin," he said at the AACR news
Provided that melatonin supplements actually contain the hormone,
Blask isn't worried about overdose.
"In human studies, melatonin has basically no toxicity," he tells
WebMD. "Now it takes very little melatonin to stimulate nighttime
sleepiness -- on the order of three-tenths of a milligram. But you
can't overdose with melatonin. People have taken gram quantities. Its
nastiest side effect is sleepiness."
View Article Sources http://
SOURCES: American Association for Cancer Research 94th Annual
Meeting, Washington, D.C., July 11-14, 2003. David E. Blask, MD, PhD,
Bassett Research Institute, Cooperstown, N.Y. David Alberts, MD,
Arizona Cancer Center.
© 2003 WebMD, Inc. All rights reserved.
* * *
The link below will direct you to the study by Prof. Denis L.
Henshaw and Dr. Russel Reiter, titled: "DO MAGNETIC FIELDS CAUSE
INCREASED RISK OF CHILDHOOD LEUKEMIA VIA MELATONI DISRUPTION?
The end of the first paragraph on page two of this 17-page study,
contains the following statement:
Melatonin may forestall onset of Parkinsons and Alzheimers and
also reduce severity ........
I am anxious to learn about the work you are doing re melatonin
since 2003. Low levels of melatonin have been found in children
diagnosed with autism-spectrum disorders as well as in Alzheimers'
patients. Is there something I can do to help you raise awareness
via Basset Healthcare, the American Association for Cancer Research,
the American Cancer Society, the Alzheimers' Association, the American
Parkinson Disease Association, the Autism Society of America, or other
organization? Society can no longer wait for information re the
importance of melatonin supplementation and the need to practice
"prudent avoidance" re electric fields due to having electric
appliances and/or telephone equipment close to sleeping humans as well
I believe all disease with the exception of the rare, truly
"inherited genetic abnormalities," are, in fact "reactive diseases/
syndromes." The facts support that more likely than not, every
health problem has the potential of being reduced by over 51% if
persons are informed they need to moe electric appliances and
telephone equipment away from beds. The percentage will most likely
increase with knowledge of melatonin's significant benefits.
Thank you for your all of your efforts. Best wishes and take
care - Joanne
Joanne C. Mueller
Guinea Pigs "R" Us
731 - 123rd Avenue N.W.
Minneapolis, Minnesota 55448-2127 USA
ARE YOU AND YOUR CHILDREN GUINEA PIGS? Letter 7-22-04 by Joanne