VCF Format Clarification

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Mike Sovic

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Jun 30, 2022, 10:27:09 AM6/30/22
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Something I don't think was clear from the documentation in the initial version of MixviR...

In cases of multiallelic sites (genomic positions with more than one variant in a sample), each variant should be split into a separate entry/line in the VCF file. So, the VCF entry(ies) for variants A & T at genomic position 1000 with Ref allele "C" in a sample should NOT look like...

chr1   1000   .    C    A,T 

But instead should look like...

chr1   1000   .    C    A
chr1   1000   .    C    T

I'll get this clarified in the next version's documentation.

         Mike
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