Family members struggled with unspecified diabetes, Islit & Cellosis Transplant Details

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(typo fixed & recent report on percents of Islit
pancreas transplants -3 types- in which trans-
plant recipients are free of exogenous insulin
at the 5-year & 10-year marks - see bottom of
Transplant area for link & insulin-free details
& links to 3 great transplant graphics)

"As a science lover who had watched family
members struggle with diabetes* and heart
disease, Kristal Acosta, now 18, dreamed
of becoming a doctor."
https://youthtoday.org/2021/07/how-a-hands-on-summer-science-program-for-underserved-youth-pivoted-online/

*Without clarifying types mentioned, it's un-
knowable which of the -7- Disparate High
Glucose Conditions (DHGCs) with -85- spe-
cific types or -1- mostly non-glucose anomaly
with -6- specific types that her family members
struggle with. See sig for links to details of ...

o 6 specific types of mostly non-glucose anom-
aly Insipidus

o all 15 specific types of rapid onset Islit

o the sole specific type of slow onset Latent
Autoimmune Islit

o the sole specific type of temporary transitory
Gestational Cellosis (weight gain caused by
pregnancy, the condition reversed within a few
weeks after the end of pregnancy -unless- the
pregnancy weight gain continues, raising the
risk of getting Preventable Cellosis)

o all 25 specific types of Ohiglucons

o all 11 specific types of Diminosis

o all 12 specific types of Neonatal Diminosis

o 20 specific types of unpreventable Cellosis

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As for weight loss & lifestyle factor changes
able to prevent (or reverse in many in first 10
years after diagnosis) DHGCs, there is -1- &
-only -1- specific type of DHGC that is preven-
table / reversible with no surgery or transplant,
Preventable Cellosis!
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Transplant

In a tiny minority of Islit individuals, pancreas
or islet cell transplants can reduce exogenous
insulin dependence for a tiny % of Islit indivi-
duals (< 1%) who are at high risk of sequelae
& qualify, though success rate decreases over
time, from no success which includes risk of ...

... death, to short to length of time variable with
very few > 10 years, all requiring risky immuno-
suppressants to try to avoid transplant rejection.

10% of Cellosis individuals are eligible to get a
pancreas transplant (see Pancreas Transplant
below).

~~~

Islet Cell Transplant (in clinical trials)
https://www.healthline.com/diabetesmine/beta-cell-transplantation-for-diabetes#Side-effects-range-from-mild-to-nasty

o 1 year post-transplant, ~75% still “insulin-free.”
o 2 years post-transplant, ~40-50% still “insulin-free.”
o 3 years post-transplant, ~10-30% still “insulin-free.”
o 4 years & greater, no information provided, though
some info on multiple transplants provided.

~~~

Pancreas Transplant (~1,000 per year)
https://www.mayoclinic.org/tests-procedures/pancreas-transplant/about/pac-20384783

About 10% done in Cellosis individuals with both
low insulin resistance & low continued insulin pro-
duction, 90% done in Islit individuals with hypergly-
cemia &/or hypoglycemia lack of success in hand-
ling with exogenous insulin. Also done along with
kidney transplant in cases of severe kidney dam-
age.

See article for long lists of risks & sequelae.

See following for average lasting time & longest
lasting times for all transplants:
https://wexnermedical.osu.edu/blog/how-long-do-transplanted-organs-last

~~~

2019 Pancreas Transplant Details
(5-year survival rates)
https://srtr.transplant.hrsa.gov/annual_reports/2019/Pancreas.aspx

o Simultaneous pancreas-kidney transplants, 91.7%
o Pancreas-after-kidney transplants, 87.8%
o Pancreas transplants alone, 79.5%
o Islit, 91.1%
o Cellosis, 93.1%

~~~

Pancreas Transplants & Insulin-Free
Percentages after 5 & 10 years

Recent data (September 2020) from over 20,000
pancreas transplants performed in the USA (also
includes information on islet cell transplantation &
non-stem-cell sources of islets):
https://link.springer.com/article/10.1007/s00125-020-05184-7

Proportion of recipients who are insulin independent
5 years after pancreas transplantation is

o 73% for Simultaneous pancreas-kidney transplants
o 64% for Pancreas-after-kidney transplants
o 53% for Pancreas transplants alone

Proportion who are insulin independent 10 years post
transplantation is

o 56% for Simultaneous pancreas-kidney transplants
o 38% for Pancreas-after-kidney transplants
o 36% for Pancreas transplants alone

Current State of Pancreas, Human Islet, &
Porcine Islet Transplantation & Considerations
https://tinyurl.com/PancreasHumanIsletPigIslitTran

Islet Cell Transplant - Humans (Pig in future)
https://tinyurl.com/IsletCellTransplantHuman-Pig

a) Pancreas Transplant, b) Islet Cell Transplant
https://tinyurl.com/a-PancreasTran-b-IsletCellTran
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Pro-Humanist FREELOVER, Insulinitis (Islit)
since age 5, got it in March 1961
https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

C.ure I.nsulinitis A.ssociation
ASAP! https://prohuman.net/cureinsulinitisassociation.htm

Glucose Anomalies Research regarding
Potential Cures / Improvements in Treatments
The Sooner The Better! https://prohuman.net/glucoseanomaliesresearch.htm

- - -

The old confusing way which all-too-often
involves folks using the diabetes / diabetic
words without a clarifier:

diabetes / diabetic without a clarifier,
diabetes / diabetic guessing required
https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

- - -

Logic and reasoning behind ceasing using
diabetes & diabetic & reactive hypoglycemia
words and phrases, replacing all that with
vastly superior names, ending diabetes &
diabetic & reactive hypoglycemia confusion,
misleading, & misunderstanding:

Diabetes Bubble / Diabetes Bubble Burst
Splendid! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

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Disparate High Glucose Conditions,
DHGCs, 7 disparate categories of
unpreventability / nonreversibility
of all-but-one of the specific types
of DHGCs (thus far, research actively
trying to change that):

o 15 specific types of rapid-onset Insul-
initis (Islit), unpreventable & nonrevers-
ible (thus far), the overwhelming majority
with Islit have Insulitis Islit (sometimes
called type 1 diabetes, often confusingly
called diabetes with no clarifier)
https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

14 specific types of Islit are not caused
by Insulitis, present in a small minority
of those with Islit.

o 1 specific type of slow-onset Islit, Latent
Autoimmune Islit, also unpreventable &
nonreversible (thus far) (sometimes called
latent autoimmune diabetes in adults, often
confusingly called diabetes with no clarifier)

o Preventable Cellosis is the only specific
type of DHGC that is preventable & revers-
ible (in many, sometimes it's called type 2
diabetes, often confusingly called diabetes
with no clarifier)

Risk for Preventable Cellosis, Hypertension,
& Cardiovascular Disease increases as one's
weight increases but BMI risk increases at
lower BMI levels in non-white individuals:
https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html

PreCellosis (often confusingly called pre-
diabetes with no clarifier) is the oft-times
preventable & reversible Cellosis precondi-
tion that all-too-often the overwhelming ma-
jority having it are unaware they have it

o 20 specific types of Cellosis, unpreven-
table & nonreversible (thus far, sometimes
called type 2 diabetes, all-too-often con-
fusingly called diabetes with no clarifier)

o 1 specific type of DHGC only occurring
in the late stage of impregnation in women,
a type that's transient but that increases
risk of later getting Cellosis, that ...

... condition called Gestational Cellosis
(sometimes called gestational diabetes,
sometimes confusingly called diabetes with
no clarifier).

o 11 specific types of Diminosis (new name
created in 2010 for a monogenic condition
> age 6 months that sometimes is called
maturity onset diabetes of the young, some-
times confusingly called diabetes with no
clarifier), unpreventable & non-reversible
(thus far).

o 12 specific types of Neonatal Diminosis
(new name created in 2010 for a monogenic
condition at age < or = 6 months that some-
times is called neonatal diabetes, sometimes
confusingly called diabetes with no ...

... clarifier), 8 types are permanent & unpre-
ventable & nonreversible (thus far); 4 specific
types are transient but can recur.

o 25 specific types of Ohiglucons (new name
created in 2010 for other diabetes mellitus,
but often confusingly called diabetes with
no clarifier).

23 specific types are totally unpreventable.

Hemochromatosis Ohiglucon, is only preventa-
ble if Hemochromatosis is found and treated
before it damages the pancreas.

Immunosuppressants Ohiglucon, caused after
a transplant with the required use of immun-
osuppressants, 50% is temporary, but if it
persists for over a year, most likely the condi-
tion is permanent.

If endogenous insulin production is near-totally
to totally lost & does not recover after immuno-
suppressants dosages reduced, it causes Im-
munosuppressants Islit.

- - -

A mostly Non-Glucose Anomaly, Insipidus, it's
also unpreventable & nonreversible (thus far):

o 6 specific types of Insipidus (new name
created in 2010 for diabetes insipidus, some-
times confusingly called diabetes with no clar-
ifier), 4 specific types don't include high glucose
& are unpreventable & nonreversible (thus far),
2 specific rare types do include high glucose &
are unpreventable & nonreversible (thus far).

- - -

The following condition is apart from the
diabetes confusion problem, but has confu-
sion issues of its own.

A Low Glucose Condition, Hut:

o The 21 specific types of Hut (new name
created in 2010 for Hypoglycemia Uncaused
by Treatments for High Glucose, often con-
fusingly called reactive hypoglycemia, con-
fusing in that it does not occur as a reac-
tion to treatment for High Glucose; one ...

... form sometimes called hyperinsulinism),
some specific types are preventable & rever-
sible, some aren't (thus far).

- - -

Stop Diabetes/Diabetic Confusion
with New Superior Clarifying Terms
https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

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