Google Groups no longer supports new Usenet posts or subscriptions. Historical content remains viewable.
Dismiss

Wonder pill that makes you skinny WITHOUT dieting moves one step closer to reality

6 views
Skip to first unread message

_

unread,
Mar 23, 2023, 4:07:26 PM3/23/23
to
1) The pill isn't a pill, it's injections, & it's
thus far only been tested in mice.

2) They are developing a pill version of
the drug and hope to start human trials
this year.

3) The drug is not being developed to
deal with Cellosis (new clarifying name
for type 2 diabetes) but a side effect of
the drug is reduction in risk of getting
Cellosis.

4) References to weight loss in the art-
icle, unclear if the drug induces weight
loss or simply prevents weight gain, so
the "makes you skinny" part of the title
may be exaggerating the actual impact
of the drug.

---
March 22 2023
https://www.dailymail.co.uk/health/article-11889987/Wonder-pill-makes-skinny-WITHOUT-dieting-exercising.html
---

... The drug — named CPACC — is a small
molecule that works by inhibiting the uptake
of magnesium by mitochondria in cells. The
team is now looking to patent the drug, but
warn it may still be years before it reaches
pharmacies. ...

~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

Pro-Humanist FREELOVER, Insulinitis (Islit)
since age 5, got it in March 1961
https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

C.ure I.nsulinitis A.ssociation
ASAP! https://prohuman.net/cureinsulinitisassociation.htm

Glucose Anomalies Research regarding
Potential Cures / Improvements in Treatments
The Sooner The Better! https://prohuman.net/glucoseanomaliesresearch.htm

- - -

The old confusing way which all-too-often
involves folks using the diabetes / diabetic
words without a clarifier:

diabetes / diabetic without a clarifier,
diabetes / diabetic guessing required
https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg

- - -

Logic and reasoning behind ceasing using
diabetes & diabetic & reactive hypoglycemia
words and phrases, replacing all that with
vastly superior names, ending diabetes &
diabetic & reactive hypoglycemia confusion,
misleading, & misunderstanding:

Diabetes Bubble / Diabetes Bubble Burst
Splendid! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm

- - -

Disparate High Glucose Conditions,
DHGCs, 7 disparate categories of
unpreventability / nonreversibility
of all-but-one of the specific types
of DHGCs (thus far, research actively
trying to change that):

o 15 specific types of rapid-onset Insul-
initis (Islit), unpreventable & nonrevers-
ible (thus far), the overwhelming majority
with Islit have Insulitis Islit (sometimes
called type 1 diabetes, often confusingly
called diabetes with no clarifier)
https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg

14 specific types of Islit are not caused
by Insulitis, present in a small minority
of those with Islit.

o 1 specific type of slow-onset Islit, Latent
Autoimmune Islit, also unpreventable &
nonreversible (thus far) (sometimes called
latent autoimmune diabetes in adults, often
confusingly called diabetes with no clarifier)

o Preventable Cellosis is the only specific
type of DHGC that is preventable & revers-
ible (in many, sometimes it's called type 2
diabetes, often confusingly called diabetes
with no clarifier)

Risk for Preventable Cellosis, Hypertension,
& Cardiovascular Disease increases as one's
weight increases but BMI risk increases at
lower BMI levels in non-white individuals:
https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html

PreCellosis (often confusingly called pre-
diabetes with no clarifier) is the oft-times
preventable & reversible Cellosis precondi-
tion that all-too-often the overwhelming ma-
jority having it are unaware they have it

o 20 specific types of Cellosis, unpreven-
table & nonreversible (thus far, sometimes
called type 2 diabetes, all-too-often con-
fusingly called diabetes with no clarifier)

o 1 specific type of DHGC only occurring
in the late stage of impregnation in women,
a type that's transient but that increases
risk of later getting Cellosis, that ...

... condition called Gestational Cellosis
(sometimes called gestational diabetes,
sometimes confusingly called diabetes with
no clarifier).

o 11 specific types of Diminosis (new name
created in 2010 for a monogenic condition
> age 6 months that sometimes is called
maturity onset diabetes of the young, some-
times confusingly called diabetes with no
clarifier), unpreventable & non-reversible
(thus far).

o 12 specific types of Neonatal Diminosis
(new name created in 2010 for a monogenic
condition at age < or = 6 months that some-
times is called neonatal diabetes, sometimes
confusingly called diabetes with no ...

... clarifier), 8 types are permanent & unpre-
ventable & nonreversible (thus far); 4 specific
types are transient but can recur.

o 25 specific types of Ohiglucons (new name
created in 2010 for other diabetes mellitus,
but often confusingly called diabetes with
no clarifier).

23 specific types are totally unpreventable.

Hemochromatosis Ohiglucon, is only preventa-
ble if Hemochromatosis is found and treated
before it damages the pancreas.

Immunosuppressants Ohiglucon, caused after
a transplant with the required use of immun-
osuppressants, 50% is temporary, but if it
persists for over a year, most likely the condi-
tion is permanent.

If endogenous insulin production is near-totally
to totally lost & does not recover after immuno-
suppressants dosages reduced, it causes Im-
munosuppressants Islit.

- - -

A mostly Non-Glucose Anomaly, Insipidus, it's
also unpreventable & nonreversible (thus far):

o 6 specific types of Insipidus (new name
created in 2010 for diabetes insipidus, some-
times confusingly called diabetes with no clar-
ifier), 4 specific types don't include high glucose
& are unpreventable & nonreversible (thus far),
2 specific rare types do include high glucose &
are unpreventable & nonreversible (thus far).

- - -

The following condition is apart from the
diabetes confusion problem, but has confu-
sion issues of its own.

A Low Glucose Condition, Hut:

o The 21 specific types of Hut (new name
created in 2010 for Hypoglycemia Uncaused
by Treatments for High Glucose, often con-
fusingly called reactive hypoglycemia, con-
fusing in that it does not occur as a reac-
tion to treatment for High Glucose; one ...

... form sometimes called hyperinsulinism),
some specific types are preventable & rever-
sible, some aren't (thus far).

- - -

Stop Diabetes/Diabetic Confusion
with New Superior Clarifying Terms
https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms

~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~

_

unread,
Apr 11, 2023, 11:11:26 AM4/11/23
to
Follow-up:

Is this drug too good to be true?

Time will tell.

- - -
April 10 2023

New Weight Loss Drug Works Despite
a High-Sugar Diet
https://healthnews.com/news/weight-loss-on-a-high-sugar-diet/
- - -

Photo implying that use of the drug
would lead to large weight loss:
https://media.healthnews.com/images/featured/2023/04/Shutterstock_2247646277.jpg

... CPACC ... restricts the amount of magnesium
delivered to the energy-producing parts of cells
known as mitochondria.

Although magnesium is a critical element for
good health along with calcium, sodium, and
potassium, too much magnesium can slow
down the energy production in mitochondria,
leading to less efficient sugar and fat metab-
olism.

When scientists deleted the gene MRS2 in mice
that promotes magnesium absorption into the
mitochondria, the rodent’s metabolism increased
— resulting in weight loss and no sign of fatty liver
disease. CPACC — a small, synthesized molecule —
produces the same results.

... Although the results of this mouse study appear
promising, the scientists still need to develop an
MRS2-modulating molecule for research involving
human participants.

In addition, the study authors say that the MRS2
channel is expressed widely throughout the body.
Therefore, investigations are needed to examine
the effects modulating MRS2 could have on other
organs, including the brain, heart, kidneys, lungs,
and muscles.

On Thursday, March 23, 2023 at 3:07:26 PM UTC-5, _ wrote:

.> 1) The pill isn't a pill, it's injections, & it's
.> thus far only been tested in mice.
.>
.> 2) They are developing a pill version of
.> the drug and hope to start human trials
.> this year.
.>
.> 3) The drug is not being developed to
.> deal with Cellosis (new clarifying name
.> for type 2 diabetes) but a side effect of
.> the drug is reduction in risk of getting
.> Cellosis.
.>
.> 4) References to weight loss in the art-
.> icle, unclear if the drug induces weight
.> loss or simply prevents weight gain, so
.> the "makes you skinny" part of the title
.> may be exaggerating the actual impact
.> of the drug.
.>
.> ---
.> March 22 2023
.> https://www.dailymail.co.uk/health/article-11889987/Wonder-pill-makes-skinny-WITHOUT-dieting-exercising.html
.> ---
.>
.> ... The drug — named CPACC — is a small
.> molecule that works by inhibiting the uptake
.> of magnesium by mitochondria in cells. The
.> team is now looking to patent the drug, but
.> warn it may still be years before it reaches
.> pharmacies. ...
.>
.> ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
.>
.> Pro-Humanist FREELOVER, Insulinitis (Islit)
.> since age 5, got it in March 1961
.> https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg
.>
.> C.ure I.nsulinitis A.ssociation
.> ASAP! https://prohuman.net/cureinsulinitisassociation.htm
.>
.> Glucose Anomalies Research regarding
.> Potential Cures / Improvements in Treatments
.> The Sooner The Better! https://prohuman.net/glucoseanomaliesresearch.htm
.>
.> - - -
.>
.> The old confusing way which all-too-often
.> involves folks using the diabetes / diabetic
.> words without a clarifier:
.>
.> diabetes / diabetic without a clarifier,
.> diabetes / diabetic guessing required
.> https://prohuman.net/pix2/diabetesdiabeticguessinggame.jpg
.>
.> - - -
.>
.> Logic and reasoning behind ceasing using
.> diabetes & diabetic & reactive hypoglycemia
.> words and phrases, replacing all that with
.> vastly superior names, ending diabetes &
.> diabetic & reactive hypoglycemia confusion,
.> misleading, & misunderstanding:
.>
.> Diabetes Bubble / Diabetes Bubble Burst
.> Splendid! https://prohuman.net/diabetesbubblediabetesbubbleburst.htm
.>
.> - - -
.>
.> Disparate High Glucose Conditions,
.> DHGCs, 7 disparate categories of
.> unpreventability / nonreversibility
.> of all-but-one of the specific types
.> of DHGCs (thus far, research actively
.> trying to change that):
.>
.> o 15 specific types of rapid-onset Insul-
.> initis (Islit), unpreventable & nonrevers-
.> ible (thus far), the overwhelming majority
.> with Islit have Insulitis Islit (sometimes
.> called type 1 diabetes, often confusingly
.> called diabetes with no clarifier)
.> https://prohuman.net/pix2/new_superior_clarifying_name_is_INSULINITIS.jpg
.>
.> 14 specific types of Islit are not caused
.> by Insulitis, present in a small minority
.> of those with Islit.
.>
.> o 1 specific type of slow-onset Islit, Latent
.> Autoimmune Islit, also unpreventable &
.> nonreversible (thus far) (sometimes called
.> latent autoimmune diabetes in adults, often
.> confusingly called diabetes with no clarifier)
.>
.> o Preventable Cellosis is the only specific
.> type of DHGC that is preventable & revers-
.> ible (in many, sometimes it's called type 2
.> diabetes, often confusingly called diabetes
.> with no clarifier)
.>
.> Risk for Preventable Cellosis, Hypertension,
.> & Cardiovascular Disease increases as one's
.> weight increases but BMI risk increases at
.> lower BMI levels in non-white individuals:
.> https://prohuman.net/pix2/BMI-WaistCircumference-Cellosis&Hypertension&CardiovascularDisease-Risk.jpg
.> https://medicalxpress.com/news/2021-05-bmi-offs-obesity-diabetes-non-white.html
.>
.> PreCellosis (often confusingly called pre-
.> diabetes with no clarifier) is the oft-times
.> preventable & reversible Cellosis precondi-
.> tion that all-too-often the overwhelming ma-
.> jority having it are unaware they have it
.>
.> o 20 specific types of Cellosis, unpreven-
.> table & nonreversible (thus far, sometimes
.> called type 2 diabetes, all-too-often con-
.> fusingly called diabetes with no clarifier)
.>
.> o 1 specific type of DHGC only occurring
.> in the late stage of impregnation in women,
.> a type that's transient but that increases
.> risk of later getting Cellosis, that ...
.>
.> ... condition called Gestational Cellosis
.> (sometimes called gestational diabetes,
.> sometimes confusingly called diabetes with
.> no clarifier).
.>
.> o 11 specific types of Diminosis (new name
.> created in 2010 for a monogenic condition
.> age 6 months that sometimes is called
.> maturity onset diabetes of the young, some-
.> times confusingly called diabetes with no
.> clarifier), unpreventable & non-reversible
.> (thus far).
.>
.> o 12 specific types of Neonatal Diminosis
.> (new name created in 2010 for a monogenic
.> condition at age < or = 6 months that some-
.> times is called neonatal diabetes, sometimes
.> confusingly called diabetes with no ...
.>
.> ... clarifier), 8 types are permanent & unpre-
.> ventable & nonreversible (thus far); 4 specific
.> types are transient but can recur.
.>
.> o 25 specific types of Ohiglucons (new name
.> created in 2010 for other diabetes mellitus,
.> but often confusingly called diabetes with
.> no clarifier).
.>
.> 23 specific types are totally unpreventable.
.>
.> Hemochromatosis Ohiglucon, is only preventa-
.> ble if Hemochromatosis is found and treated
.> before it damages the pancreas.
.>
.> Immunosuppressants Ohiglucon, caused after
.> a transplant with the required use of immun-
.> osuppressants, 50% is temporary, but if it
.> persists for over a year, most likely the condi-
.> tion is permanent.
.>
.> If endogenous insulin production is near-totally
.> to totally lost & does not recover after immuno-
.> suppressants dosages reduced, it causes Im-
.> munosuppressants Islit.
.>
.> - - -
.>
.> A mostly Non-Glucose Anomaly, Insipidus, it's
.> also unpreventable & nonreversible (thus far):
.>
.> o 6 specific types of Insipidus (new name
.> created in 2010 for diabetes insipidus, some-
.> times confusingly called diabetes with no clar-
.> ifier), 4 specific types don't include high glucose
.> & are unpreventable & nonreversible (thus far),
.> 2 specific rare types do include high glucose &
.> are unpreventable & nonreversible (thus far).
.>
.> - - -
.>
.> The following condition is apart from the
.> diabetes confusion problem, but has confu-
.> sion issues of its own.
.>
.> A Low Glucose Condition, Hut:
.>
.> o The 21 specific types of Hut (new name
.> created in 2010 for Hypoglycemia Uncaused
.> by Treatments for High Glucose, often con-
.> fusingly called reactive hypoglycemia, con-
.> fusing in that it does not occur as a reac-
.> tion to treatment for High Glucose; one ...
.>
.> ... form sometimes called hyperinsulinism),
.> some specific types are preventable & rever-
.> sible, some aren't (thus far).
.>
.> - - -
.>
.> Stop Diabetes/Diabetic Confusion
.> with New Superior Clarifying Terms
.> https://www.change.org/stopdiabetesdiabeticconfusionwithNewSuperiorClarifyingTerms
.>
.> ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~
0 new messages