I'm thinking of doing LFP recording with open-ephys system while calcium imaging with the miniscope v4. But the miniscope's circuit board is exposed and located very close to the headstage used for ephys recordings, starting imaging acquisition introduces tons of noise to LFP recording. I am struggling to find a proper way to ground the miniscope. I have tried:
1)
I attempted to connect several pins on the miniscope v4 circuit board to ground. However, this did not noticeably improve the noise issue.
And when I ground some pins, miniscope shut down. Due to the lack of access to an accurate circuit diagram for the v4 board, I'm unsure whether the connections were made to the correct ground pins.
2)
I insulated the miniscope and wrapped it in grounded aluminum foil, which helped reduce the noise to some extent. However, I’m still unable to obtain reliable electrophysiological signals.
Given the persistent noise issue, I would sincerely appreciate any advice or guidance from experts on how to correctly ground the miniscope v4 to ensure reliable electrophysiological recordings.