Or so it seems...
Salt or cocaine, a fix is a basic instinct
16 July 2011 - NewScientist.com
PRIMORDIAL instincts that drive animals to seek out salt
may be governed by the same mechanism that drives drug addicts to hunt
down their fix. Researchers deprived mice and rats of salt, then offered
them salty water to drink. After killing the animals they examined gene
activity in the hypothalamus, the brain's "reward" centre. They found
that gratification genes had been activated - the same genes that are
active in cocaine and heroin addicts when their craving has been
satisfied.
If the team used a drug to block the effects of dopamine, the
neurotransmitter associated with feelings of enjoyment, the animals did
not drink the salty water. This suggests that the urge to seek out salt
is indeed linked to the reward mechanism (
Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.1109199108).
The discovery might open up new ways to treat addiction. "We're not
saying the new data tells us how to cure addiction, but it does point to
new avenues of investigation," says team member Derek Denton of the
University of Melbourne, Australia.
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