Humm,weinre client is webkit base browser only.please remote debug with Chrome,and make sure the MIHTool HTTP Server is ON(dont let the screen dim,you may set it keep awake by switch the button to ON),if the problem still,you can clear the site data of the HTTP Server's site(the ip address) from your browser.
If those not help you,please let me know more information,like device(iPhone or iPad,iOS version...).