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PURAVIVE Side Effects Blood Pressure Medication - BEWARE!!!

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Drew Hamilton

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Feb 16, 2024, 11:27:32 PM2/16/24
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PURAVIVE Side Effects: Blood Pressure Medication

PURAVIVE (dexmedetomidine) is a medication used to treat high blood pressure.

Common side effects include dizziness, headache, and nausea.

More serious side effects can include bradycardia, hypotension, and respiratory depression.

Potential drug interactions and precautions should be considered.

It is important to follow the dosing instructions and consult with a healthcare professional regarding any concerns.

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Introduction
PURAVIVE (dexmedetomidine) is a medication used to treat high blood pressure (hypertension). It is a selective alpha-2 adrenergic receptor agonist that works by decreasing sympathetic outflow from the central nervous system, resulting in decreased blood pressure. PURAVIVE is typically used as an adjunct to other antihypertensive medications.

Common Side Effects
The most common side effects of PURAVIVE include:

Dizziness

Headache

Nausea

Dry mouth

Constipation

Fatigue

Weakness

More Serious Side Effects
Although less common, PURAVIVE can also cause more serious side effects, including:

Bradycardia: Slowed heart rate, which can lead to dizziness, fainting, or even cardiac arrest.

Hypotension: Low blood pressure, which can cause dizziness, fainting, or organ damage.

Respiratory Depression: Shallow or slow breathing, which can be life-threatening.

Other potential side effects include:
Confusion
Hallucinations
Tremor
Visual disturbances
Seizures
Coma

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Drug Interactions
PURAVIVE can interact with certain medications, including:

Anesthetics: Can enhance the sedative effects of PURAVIVE.

Antidepressants: Can increase the risk of serotonin syndrome.

Antihypertensive Medications: Can potentiate the blood pressure-lowering effects of PURAVIVE.

Cytochrome P450 (CYP450) Inhibitors: Can increase the levels of PURAVIVE in the body.

Precautions
PURAVIVE should be used with caution in patients with:

Severe heart failure: Can worsen the condition.

Severe liver disease: Can increase the risk of side effects.

Respiratory depression: Can worsen the condition.

Hypovolemia: Can cause severe hypotension.

Elderly patients: May be more sensitive to the effects of PURAVIVE.

Usage
PURAVIVE is typically taken orally once or twice daily. It is important to take PURAVIVE exactly as prescribed by your healthcare provider and to follow the dosing instructions carefully. Do not increase or decrease the dose without consulting your healthcare provider.

Inform your healthcare provider about all medications you are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements. Discuss any allergies or previous adverse reactions to medications.

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Frequently Asked Questions
Q: What are the potential long-term side effects of PURAVIVE?

A: Long-term side effects of PURAVIVE are not well established. However, it is important to monitor for the potential side effects listed above, especially in patients taking PURAVIVE for prolonged periods.

Q: Can PURAVIVE be used during pregnancy?

A: PURAVIVE is not recommended for use during pregnancy. There are limited studies on the safety of PURAVIVE in pregnant women, and it is classified as Pregnancy Category C.

Q: Can PURAVIVE be used while breastfeeding?

A: PURAVIVE is excreted in breast milk. It is not recommended to use PURAVIVE while breastfeeding.

Q: What should I do if I experience severe side effects from PURAVIVE?

A: If you experience any severe side effects, such as bradycardia, hypotension, or respiratory depression, seek immediate medical attention.



External Links:
PURAVIVE (dexmedetomidine) Patient Information

Dexmedetomidine - National Library of Medicine

Dexmedetomidine: A Review of Its Pharmacology and Clinical Applications


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