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Jan 28, 2024, 5:10:18 PM1/28/24
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what is microdosing

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Microdosing, or micro-dosing, is a technique for studying the behaviour of drugs in humans through the administration of doses so low they are unlikely to produce whole-body effects, but high enough to allow the cellular response to be studied

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Tips for Microdosing

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Use an accurate scale if you don’t have a pre-measured dose.
Take your first dose on an average, non-work day when you feel physically and mentally well.
Ensure your environment is calm and safe, with few, if any, demands on your time.
Stick to your chosen protocol for at least four to eight or ten weeks.
Start with a minimal dose for a few days. If needed, adjust the amount up or down for another few days. Keep tweaking the dose as needed until you achieve the desired results.
Microdose in the morning, as taking a dose later may disrupt regular sleep patterns.
Don’t take alcohol or other mind-altering drugs concurrently, at least initially. Some people find CBD – a non-psychoactive chemical found in marijuana – to help with the experience.
As mentioned, maintain a microdosing journal including details on your diet, activities, other alcohol or drug use, and OTC medications, along with specifics on the dose, time taken, results, and any concerns.
Don’t rush the process. Give your protocol and dose time to work.

Psychedelic Effects versus Microdosing
Hallucinogens

The National Institute on Drug Abuse provides the following short-term general effects of hallucinogens at a psychoactive dose:

Sensory Effects

Hallucinations, including seeing, hearing, touching, or smelling things in a distorted way or perceiving things that are not real.
Intensified feelings and sensory experiences, including brighter colors and sharper sounds.
Mixed senses, as the person “sees” sounds or “hears” colors.
Changes in time perception, where people report that time moves very slowly.
Physical Effects

Increased energy and heart rate.
Nausea.
Long-term effects can include persistent hallucinations and psychosis. Although these effects are more common in those with a preexisting mental disorder, they can occur in anyone, even after their first time using a hallucinogen.

A psychedelic high's effects can be intense, frightening, and even deadly. Terrifying flashbacks, nightmares, extreme anxiety, paranoia, and medical emergencies like seizures, comas, or heart attacks can occur.

Effects of Microdosing Hallucinogenic Substances
Most experts consider microdosing to be safe, with few, if any, adverse side effects. Some individuals may be more sensitive to the substance than others and experience fatigue, mild discomfort, and increased anxiety.

Beneficial effects of microdosing may include:

Heightened focus, creativity, productivity, and energy.
Decreased anxiety, depression, or stress.
Less social anxiety.
Reduced menstrual pain.
Emotional openness.
Increased spiritual awareness.
Reduced cravings for addictive substances.
Doctors may advise against microdosing for people with the following:

Autism (see note below)
Colorblindness - some colorblind people dropped out of a study due to uncomfortable “visual effects"
Past trauma – while psychedelic doses may trigger or worsen PTSD or other anxiety disorders, studies evaluating microdosing to heal past trauma are encouraging
Physical illness
Children in their care
History of psychotic disorders like bipolar disorder or schizophrenia
While some doctors advise those on the autism spectrum not to microdose, several studies and surveys of autistic adults found the practice can be beneficial. A pilot trial published in Psychopharmacology demonstrated “rapid and durable improvement in social anxiety symptoms in autistic adults following MDMA-assisted psychotherapy.”

Although studies have found microdosing, especially with ketamine, to deliver positive results for most people with anxiety disorders, some may experience worsening symptoms.


Psychedelic Effects versus Microdosing
Hallucinogens

The National Institute on Drug Abuse provides the following short-term general effects of hallucinogens at a psychoactive dose:

Sensory Effects

Hallucinations, including seeing, hearing, touching, or smelling things in a distorted way or perceiving things that are not real.
Intensified feelings and sensory experiences, including brighter colors and sharper sounds.
Mixed senses, as the person “sees” sounds or “hears” colors.
Changes in time perception, where people report that time moves very slowly.
Physical Effects

Increased energy and heart rate.
Nausea.
Long-term effects can include persistent hallucinations and psychosis. Although these effects are more common in those with a preexisting mental disorder, they can occur in anyone, even after their first time using a hallucinogen.

A psychedelic high's effects can be intense, frightening, and even deadly. Terrifying flashbacks, nightmares, extreme anxiety, paranoia, and medical emergencies like seizures, comas, or heart attacks can occur.

Effects of Microdosing Hallucinogenic Substances
Most experts consider microdosing to be safe, with few, if any, adverse side effects. Some individuals may be more sensitive to the substance than others and experience fatigue, mild discomfort, and increased anxiety.

Beneficial effects of microdosing may include:

Heightened focus, creativity, productivity, and energy.
Decreased anxiety, depression, or stress.
Less social anxiety.
Reduced menstrual pain.
Emotional openness.
Increased spiritual awareness.
Reduced cravings for addictive substances.
Doctors may advise against microdosing for people with the following:

Autism (see note below)
Colorblindness - some colorblind people dropped out of a study due to uncomfortable “visual effects"
Past trauma – while psychedelic doses may trigger or worsen PTSD or other anxiety disorders, studies evaluating microdosing to heal past trauma are encouraging
Physical illness
Children in their care
History of psychotic disorders like bipolar disorder or schizophrenia
While some doctors advise those on the autism spectrum not to microdose, several studies and surveys of autistic adults found the practice can be beneficial. A pilot trial published in Psychopharmacology demonstrated “rapid and durable improvement in social anxiety symptoms in autistic adults following MDMA-assisted psychotherapy.”

Although studies have found microdosing, especially with ketamine, to deliver positive results for most people with anxiety disorders, some may experience worsening symptoms.

/

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Jan 28, 2024, 5:23:59 PM1/28/24
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