This is mostly referring to the hidden track on 10,000 Days with Viginti Tres and Wings, and the "Holy Gift" theories. When I first heard of these a long time ago I thought it would be wonderful, but I have yet to find a flow in either of them. Are these just fans' theories about the songs or was it fully intended by the band? (If anyone does find one of these online and it works please let me know.)
Grow from seeds requires a at least one small seed region for each segment. For easy segmentation tasks you can generate these seeds fully automatically or use other tools (e.g., Thresholding and Islands / Split islands to segments). If you describe what you would like to achieve on what kind of images then we can give more specific advice.
Thank you for your time and your help. I think I misspoke indeed my goal is not really to do the segmentation of this image ( it was just an example to illustrate an issue in the grow from seed tool that I want to correct) .
You may also try Local threshold effect, which takes care of the extent (it uses whatever large extent is needed), allows setting the threshold range in the same tool (you draw a small region to specify the threshold range, then you get the complete segmentation with a single Ctrl-click):
Indices and maps are useful tools for public health advocacy and planning, and can guide policy decisions. This paper describes the development of global indices and maps depicting hidden hunger, reflecting both the prevalence of multiple micronutrient deficiencies and the associated disease burden, to serve as a tool to stimulate global efforts towards scaling up nutrition interventions. By highlighting the global hidden hunger hotspots and providing a ranking index of affected countries, the maps are expected to be useful in informing strategies for unified efforts to eliminate hidden hunger. It is anticipated that these indices and maps will enable public health scientists and policy makers to prioritize program assistance for those countries most affected by hidden hunger.
Two separate datasets were compiled for the development of hidden hunger indices and maps: i) a database of the most up-to-date national prevalence estimates of anemia, stunting, vitamin A deficiency (VAD) in pre-school aged children, and iodine deficiency (ID) in school-aged children, for 190 countries for the years 1999-2009; and ii) data of the recent DALY estimates attributed to deficiencies of iron, zinc, vitamin A, and iodine for 192 countries. Using these datasets, hidden hunger maps and indices were created by i) combining national prevalence estimates of anemia, stunting, and VAD for preschool-age, children, together with separately added estimates of ID for school-age children; and ii) combining country-wide DALY estimates attributed to deficiencies of iron, zinc, and vitamin A for the population.
Data on stunting, anemia, VAD, and ID prevalence were chosen on the basis of their contribution to hidden hunger, as well as the global availability of nationally-representative estimates. Deficiencies of folate and vitamin B12 were excluded from the dataset, due to the limited availability of national data.
In addition to micronutrient deficiency variables, national data on important proximate determinants of hidden hunger were compiled. These include the percentage of the population with inadequate dietary energy intakes estimated by the Food and Agriculture Organization (FAO), and the Human Development Index (HDI) and Multidimensional Poverty Index (MPI) of the United Nations Development Programme (UNDP) [29,30]. The HDI provides a composite measure of three basic dimensions of human development: a long and healthy life, education, and the standard of living. The MPI identifies overlapping deprivations at a household level across the same three dimensions as the HDI, and shows the average number of poor people and deprivations with which poor households contend. Countries were grouped by WHO region.
The Hidden Hunger Indices which reflected the global disease burden were computed in two different ways, as i) the total hidden-hunger-associated DALYs per 100,000 population (HHI-DBa); and ii) the total hidden-hunger-associated DALYs per country (HHI-DBu). The DALYs attributed to ID were not included in the HHI estimation due to incomplete data for several countries, its weak correlations with other micronutrient deficiencies, and its relatively small contribution to the total DALY-based HHI. The associations between HHI-PD and both HHI-DBa and indicators of human development and inadequate dietary energy intakes were examined using the Spearman rank correlation coefficient.
Globally, there were hot spots of hidden hunger, with the prevalence being alarmingly high in sub-Saharan Africa, and severe in many countries in South-Central/South-East Asia (Figure 2). Most South American countries only had a mild-to-moderate degree of hidden hunger. In many countries, ID prevalence in school-age children did not conform to the magnitude of hidden hunger. For instance, the Democratic Republic of the Congo and Liberia, both with an alarmingly high degree of hidden hunger, had low ID prevalences of 1.5% and 3.5%, respectively. In addition, in Latvia, the Russian Federation, Estonia, and Malaysia, all of which exhibited a mild degree of hidden hunger, ID prevalence was as high as 76.8, 58.6, 67.0 and 48.2%, respectively.
The maps and indices described in this paper provide much-needed information on the collective magnitude and distribution of multiple micronutrient deficiencies across the globe, and their attributed disease burden, for potential use in advocacy and planning efforts to guide health and nutrition policies. Notably, a number of countries in sub-Saharan Africa, as well as India and Afghanistan, had an alarmingly high level of hidden hunger, with stunting, IDA, and VAD all being highly prevalent amongst preschool-age children. Countries in sub-Saharan Africa, such as Sierra Leone and Niger, exhibited the highest levels of population-adjusted disease burden attributed to micronutrient deficiencies. In the 36 high-burden countries, deficiencies of micronutrients, especially vitamin A and zinc, were responsible for 2-12% of the total DALYs. In contrast, due to the large population size of South Asia, the population-unadjusted total DALYs attributed to hidden hunger were greatest in India, Bangladesh, and Pakistan.
There was a strong inverse correlation between HHI-PD and HDI, regardless of the use of only national estimates or both national and regression estimates in the calculation of HHI-PD (data not shown). As expected, countries with high HDI tended to have low HHI-PD, and vice versa. This highlights the importance of addressing hidden hunger in order to reduce general deprivation, improve health and education, and vice versa. Conversely, the HHI-PD was only weakly associated with the measure of undernourishment which reflects the proportion of populations with an inadequate energy intake. This indicates that the HHI-PD measures a form of hunger associated less with energy deficiency, and more with a lack of essential micronutrients. The current indices and maps are therefore particularly helpful while planning program assistance for populations which suffer from deficiencies of one or more micronutrients.
The DALY-based indices and maps were intended to capture the consequences of micronutrient deficiencies globally. The population-adjusted DALY rates attributed to micronutrient deficiencies were largest in sub-Saharan African countries, as was observed in hidden hunger prevalence estimates. The DALYs attributed to deficiencies of iron, vitamin A, and zinc were strongly correlated with one another (data not shown). Overall, the hidden hunger indices based on prevalence estimates and DALYs were strongly correlated (r=0.9), implying, as expected, that the disease burden due to hidden hunger tended to be greater in countries where micronutrient deficiencies were prevalent. By contrast, the population-unadjusted total disease burdens attributable to hidden hunger were greatest in countries with large populations in South Asia.
A few limitations of the indices and maps need to be considered. The indices were not comprehensive in their representation of global hidden hunger due to the limited availability of national data pertaining to key micronutrients. In the absence of biochemical indicators of zinc deficiency and the validation of the adequacy of zinc in national food supplies, national stunting prevalence was used to reflect population zinc status, recognizing that this does not reflect the true prevalence of zinc deficiency, and that multiple factors besides zinc deficiency could lead to impaired linear growth. Moreover, to arrive at national estimates of IDA, an assumption of 50-60% of anemia attributable to iron deficiency was made. These assumptions need further validation, however. The HHI-PD estimates were based on prevalence data for preschool-age children, without taking into account other important and recognized vulnerable groups, such as pregnant women. Overall, due to poor data coverage of micronutrient deficiency variables, the HHI-PD could only be estimated for approximately 60% of the countries. The prevalence estimates derived from regression methods for countries lacking national data were, at best, an approximation, which may not accurately reflect the true burden of hidden hunger. In addition, estimates of the correlation between HHI-PD and HHI-DBa must be considered with respect to the fact that there is an overlap in the data on anemia, stunting, and serum retinol used to calculate both indices.
In conclusion, more high-quality national data on the deficiency status of other key vitamins and minerals and a better estimation of zinc and iron deficiency are warranted to improve the measure of global hidden hunger. The regression estimates for anemia and VAD may need to be updated, in order to take into account more recent country prevalence of deficiencies and covariates measuring health status and development indicators. Despite these further needs, the current indices and maps capturing the burden and consequences of hidden hunger provide crucial evidence for the appropriate targeting and prioritizing of comprehensive and inclusive program assistance aiming to tackle global multiple micronutrient deficiencies. Moreover, the indices and maps are believed to serve as useful tools to call for urgent and unified efforts to stimulate relevant global advocacy efforts towards the continued scaling up of nutrition interventions.
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