Ideally, you should simply be able to say:
Plot2D.setTitle( "Line 1\nLine 2\nLine 3" )
That said, SimpleTextPainter can paint text aligned vertically to the Top, Center, or Bottom of a GlimpseLayout area. So if you don't need more than three lines, you can just add three of your own SimpleTextPainters to the GlimpseLayout defining the plot title area.
Once you do this, if you want to change the color, font, etc... of the text, you'll have to call the setter methods on the painters you created. The title methods on the Plot2D won't do anything since it thinks the title is empty.
As a side note, as long as you can get at the GlimpseLayout defining the space you want to draw in, you can always add GlimpsePainter subclasses to perform any arbitrary OpenGL rendering you want in that space. So if you want to put something different than the simple text title that Plot2D provides, that's always an option (although might involve a good bit more work/customization).