I use them, they are "almost" a drop in replacement with some caveats.
1. The micro stepping jumpers need to be changed as the default 1/16 all in for a4988 is 1/32 on the drv8825.
2. They only work when the 12v is on, and the vRef can only be set with 12v on (unlike a4988)
3. the vref needs to be set differently
Current Limit = VREF × 2 as opposed to 2.5 on a4988.
They loose their micro stepping place when the 12v goes off unlike a4988 which keeps it as long as 5v is on.
Other than that they work pretty well.