Re: Seeking help for MELTING

[Nicolas Le Novere]

Dear CHEN Xin,

You will find the software at:
https://www.ebi.ac.uk/biomodels/tools/melting/

The web interface is no longer provided. However, you can download the version 4 and 5 of the software and use them on your machine. Packages for Linux distribution Debian and Ubuntu are available.

MELTING is also provided as part of bioconductor:

https://bioconductor.org/packages/release/bioc/html/rmelting.html

An alternative in R is

https://github.com/hrbrmstr/melting5jars

MELTING has also been reimplemented in Python

https://biopython.org/docs/1.75/api/Bio.SeqUtils.MeltingTemp.html

Best regards,

On 17/09/2023 03:14, 陈鑫 wrote:
> Dear  Dr. Novère：
>
> I am a doctoral candidate of Xi'an Jiaotong University in PRC. I major in DNA computing. Recently I read your paper titled "MELTING, computing the melting temperature of nucleic acid duplex" . I found it I may help me achieve my goals in this research field.This would make a really positive contribution to my work.
> However, MELTING is not available by visiting website provided in the paper. I wonder if you would consider sending me the latest access address of MELTING by email. Perhaps you would consider this as an act of friendship between our two countries.
>
> Thank you for your kind consideration of this request.
>
> sincerely,
>
> CHEN Xin
>