New set of parameters for RNA/DNA

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nicolas.g...@cnrs.fr

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Nov 26, 2025, 8:51:53 AMNov 26
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I just discovered the following paper from the Sugimoto's lab

Banerjee et al. Improved nearest-neighbor parameters for the stability of RNA/DNA hybrids under a physiological condition. Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 12042–12054

The paper proposes a new set of NN parameters for DNA/RNA duplexes in conditions of low (physiological) salinity. I will try to add them to the repository. Although it is not clear if they can be used with the same formula (salt correction) as the Sugimoto95 ones.
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