It depends on what plugin you're using. Normally, Janus automatically sends retransmissions when receiving NACKs, and sends NACKs when incoming packets are missing. When too many of those are seen, a slow_link is notified to plugins, which can handle them if they want. In the echotest and videocall, this is done by halving the bitrate cap, using properly REMB feedback towards the browser; in particular, for the videocall plugin if a user has trouble receiving media and so is sending too many NACKs, its peer is notified and so its his bitrate that is reduced. In the videoroom, this is just notified at the application level, which might or might not want to do something about it (it currently doesn't in our demos). Same thing in the recorder plugin, which reduces the bitrate.
L.