Boxcar on QE classic - error

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rapha...@gmail.com

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Oct 30, 2018, 7:51:27 AM10/30/18
to MaxQuant.Live
Hi, I tried to do Boxcar on a QE classic. We are running Tune version 2.9 - I see in the meantime you updated the compatibility to HF/HF-X,
but maybe you have an idea to overcome this issue anyways.
When trying to connect the QE through Maxquant live we get an error (see message below)
thanks for your help



See the end of this message for details on invoking 

just-in-time (JIT) debugging instead of this dialog box.

 

************** Exception Text **************

System.NullReferenceException: Object reference not set to an instance of an object.

   at Thermo.Prometheus.FileIO.ScanInfoParser.GetNewEvent()

   at Thermo.Prometheus.FileIO.DataHeader.ReflectionBunch.CreateTranslation()

   at Thermo.Prometheus.Access.MsScanContainer.MsScanContainerImpl..ctor(InfoBag bag)

   at Thermo.Prometheus.Access.InstrumentAccess..ctor(Int32 index, RegistryInstrumentSettings settings)

   at Thermo.Prometheus.Access.InstrumentAccessIncarnation.GetImplementation(Int32 instrument, RegistryInstrumentSettings settings)

   at Thermo.Prometheus.Access.InstrumentAccessIncarnation..ctor(Int32 instrument, RegistryInstrumentSettings settings)

   at Thermo.Prometheus.Access.InstrumentAccessContainerClr.Get(Int32 index)

   at MqLiveLib.Instruments.ThermoInstrument.DoConnect(ScanQueue scanQueue) in D:\code\net\net\MqLiveLib\Instruments\ThermoInstrument.cs:line 241

   at MqLiveLib.MqLiveEngine.ConnectInstrument() in D:\code\net\net\MqLiveLib\MqLiveEngine.cs:line 53

   at MqLive.MqLiveForm.button2_Click(Object sender, EventArgs e)

   at System.Windows.Forms.Control.OnClick(EventArgs e)

   at System.Windows.Forms.Button.OnClick(EventArgs e)

   at System.Windows.Forms.Button.OnMouseUp(MouseEventArgs mevent)

   at System.Windows.Forms.Control.WmMouseUp(Message& m, MouseButtons button, Int32 clicks)

   at System.Windows.Forms.Control.WndProc(Message& m)

   at System.Windows.Forms.ButtonBase.WndProc(Message& m)

   at System.Windows.Forms.Button.WndProc(Message& m)

   at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)

 

 

************** Loaded Assemblies **************

mscorlib

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.NET/Framework64/v4.0.30319/mscorlib.dll

----------------------------------------

MqLive

    Assembly Version: 1.0.0.0

    Win32 Version: 1.0.0.0

    CodeBase: file:///C:/MqLive_0.99/MqLive.exe

----------------------------------------

System.Windows.Forms

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Windows.Forms/v4.0_4.0.0.0__b77a5c561934e089/System.Windows.Forms.dll

----------------------------------------

System

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System/v4.0_4.0.0.0__b77a5c561934e089/System.dll

----------------------------------------

System.Drawing

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Drawing/v4.0_4.0.0.0__b03f5f7f11d50a3a/System.Drawing.dll

----------------------------------------

MqLiveLib

    Assembly Version: 1.0.0.0

    Win32 Version: 1.0.0.0

    CodeBase: file:///C:/MqLive_0.99/lib/MqLiveLib.DLL

----------------------------------------

System.Core

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Core/v4.0_4.0.0.0__b77a5c561934e089/System.Core.dll

----------------------------------------

System.Configuration

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Configuration/v4.0_4.0.0.0__b03f5f7f11d50a3a/System.Configuration.dll

----------------------------------------

System.Xml

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Xml/v4.0_4.0.0.0__b77a5c561934e089/System.Xml.dll

----------------------------------------

System.Design

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Design/v4.0_4.0.0.0__b03f5f7f11d50a3a/System.Design.dll

----------------------------------------

Microsoft.GeneratedCode

    Assembly Version: 1.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Xml/v4.0_4.0.0.0__b77a5c561934e089/System.Xml.dll

----------------------------------------

API-1.0

    Assembly Version: 1.0.0.27

    Win32 Version: 1.0.0.27

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/API-1.0/1.0.0.27__4928eef831aedd73/API-1.0.dll

----------------------------------------

ESAPI-1.0

    Assembly Version: 1.0.0.27

    Win32 Version: 1.0.0.27

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ESAPI-1.0/1.0.0.27__4928eef831aedd73/ESAPI-1.0.dll

----------------------------------------

ExactiveAccess

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ExactiveAccess/2.9.0.2926__afdcd0a06562c881/ExactiveAccess.dll

----------------------------------------

ExactiveManager

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ExactiveManager/2.9.0.2926__afdcd0a06562c881/ExactiveManager.dll

----------------------------------------

Exactive

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/Exactive/2.9.0.2926__afdcd0a06562c881/Exactive.dll

----------------------------------------

ESAPI-1.1

    Assembly Version: 1.1.0.1

    Win32 Version: 1.1.0.1

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ESAPI-1.1/1.1.0.1__4928eef831aedd73/ESAPI-1.1.dll

----------------------------------------

VI-1.0

    Assembly Version: 1.0.0.0

    Win32 Version: 1.0.0.0

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/VI-1.0/1.0.0.0__4704bcc40e859f23/VI-1.0.dll

----------------------------------------

ME.ILink-1.7

    Assembly Version: 1.7.0.1

    Win32 Version: 1.7.0.1

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ME.ILink-1.7/1.7.0.1__a28bcc6ed5efca08/ME.ILink-1.7.dll

----------------------------------------

ExactiveVersion

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ExactiveVersion/2.9.0.2926__afdcd0a06562c881/ExactiveVersion.dll

----------------------------------------

System.Runtime.Remoting

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_MSIL/System.Runtime.Remoting/v4.0_4.0.0.0__b77a5c561934e089/System.Runtime.Remoting.dll

----------------------------------------

ExactiveLicensing

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ExactiveLicensing/2.9.0.2926__afdcd0a06562c881/ExactiveLicensing.dll

----------------------------------------

System.Web

    Assembly Version: 4.0.0.0

    Win32 Version: 4.6.1590.0 built by: NETFXREL2

    CodeBase: file:///C:/Windows/Microsoft.Net/assembly/GAC_64/System.Web/v4.0_4.0.0.0__b03f5f7f11d50a3a/System.Web.dll

----------------------------------------

ExactiveIoWrapper

    Assembly Version: 2.9.0.2926

    Win32 Version: 2.9.0.2926

    CodeBase: file:///C:/Windows/assembly/GAC_MSIL/ExactiveIoWrapper/2.9.0.2926__afdcd0a06562c881/ExactiveIoWrapper.dll

----------------------------------------

 

************** JIT Debugging **************

To enable just-in-time (JIT) debugging, the .config file for this

application or computer (machine.config) must have the

jitDebugging value set in the system.windows.forms section.

The application must also be compiled with debugging

enabled.

 

For example:

 

<configuration>

    <system.windows.forms jitDebugging="true" />

</configuration>

 

When JIT debugging is enabled, any unhandled exception

will be sent to the JIT debugger registered on the computer

rather than be handled by this dialog box.

 

 

 

Christoph Wichmann

unread,
Nov 1, 2018, 8:50:56 AM11/1/18
to MaxQuant.Live
Hi Raphael,
 we don't have any experience with the QE classic and we actually don't know if MaxQuant.Live works with these instruments. 
It would be helpful to know the windows version that you are running. Could you also describe when the software is crashing (which buttons did you click? what was the instrument status in Tune? Did you get any log messages in the Tune log window?)

Best, Christoph

Grace Loxley

unread,
Mar 29, 2019, 8:21:30 AM3/29/19
to MaxQuant.Live
Hi Raphael,

Did you find out what caused this? I get exactly the same message. I am attempting to connect to a QE Plus using 32-bit Windows 7 PC. When I first try to connect to the instrument manually after opening up MaxQuant.live, the warning message 'unable to load an assembly set being able to write RAW files' appears, followed by the same error message that you got. When I try to connect after this, the second error message is the only one I get. Tune recognises that MaxQuant.live has attempted to take over control, but has failed.
I have created the methods in Xcalibur that connect to the appropriate scan protocol in MaxQuant.live using magic scan. When I tried running a method, MaxQuant.live took control fine and ran the 90 minute method, but did not write the raw files beyond the 10 minute window specified in the Xcalibur method. The Tune log shows that MaxQuant.live has taken over.

Thanks,
Grace
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