1. What flight stack are you using this with?
2. You say GUIDED mode so why are you using mission items?
3. I would move to MAVLink 2. Mavlink 1 is more or less dead. Though it should not matter for this kind of thing.
What are you trying to achieve? I.e. control over a vehicle via a companion computer? Or mission planning etc.
My answer is likely to be "ask this again in the discussion forum for your flight stack, providing all the information about what you are trying to do". They will be able to tell you what commands are supported in the modes that you want to use.