Download Song Allo Allo
Cuauhtleco Scoobz
As each episode builds on previous ones, viewers are often required to have followed the series to the episode they have reached in order to understand the plot. As 'Allo 'Allo! revolved around individual story arcs spread across several episodes, the creators opted for using a comical version of the "As you remember ..." device, commonly used in serials, to act as a recap of events in the current story for the beginning of a new episode. This device within the sitcom was always conducted by René, who would open an episode by breaking the fourth wall (which Michael Bates did in It Ain't Half Hot Mum) to interact with the audience and provide a brief summary of events that had occurred previously, including notable events that had taken place, and also intermittently during episodes to make comic comments. This plot device was rare for comedy (including comedy animation), where plots are prominently gag-driven and self-contained, but its use in 'Allo 'Allo! had a major impact on audiences connecting with the characters. It also had considerable benefits for re-runs, as it allowed local TV stations who had reshuffled episodes for their schedule to ensure that their audiences could be aware of the plot events surrounding the story of the episode being broadcast.
Series five was commissioned with a view to syndicating the show in America.[22] As a result, it aired as a single long series of twenty-six episodes between September 1988 and February 1989, with each episode running only twenty-five minutes to allow for commercials. The attempts to air the show in America failed (although screening rights to the series were later sold to PBS), and so series six had only eight episodes commissioned, which aired from September 1989 onwards.
In 1986, Gorden Kaye and Vicki Michelle released a version of the hit song "Je t'aime... moi non plus". The characters of Yvette and René could be heard talking and canoodling in a comic manner whilst the familiar musical "Je t'aime..."' melody played in the background. The song got to number fifty-seven in the UK Singles Chart.[27]
The song "Allo" by Balti is a love song that expresses the longing and affection the singer has for his beloved. The lyrics are in Tunisian Arabic and the song begins with the singer addressing his loved one, saying "Allo allo, allo ya omri wenek allo ya chbebi wenek allo yal ghali wenek" which translates to "Hello, hello, hello my life, where are you, my dear, where are you my love."
Throughout the song, the singer reminisces about the past moments he shared with his beloved and yearns for her presence once again. He also talks about the challenges they faced as a couple from the jealousy of others to the distance that separates them. Despite all this, he continues to express his love and desire to reunite with her.
The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells (mTECs) to bone marrow (BM) APCs is unknown. We report that antigen was primarily transferred from mTECs to CD8α+ dendritic cells (DCs) and showed that CD36, a scavenger receptor selectively expressed on CD8α+ DCs, mediated the transfer of cell-surface, but not cytoplasmic, antigens. The absence of CD8α+ DCs or CD36 altered thymic T cell selection, as evidenced by TCR repertoire analysis and the loss of allo-tolerance in murine allogeneic BM transplantation (allo-BMT) studies. Decreases in these DCs and CD36 expression in peripheral blood of human allo-BMT patients correlated with graft-versus-host disease. Our findings suggest that CD36 facilitates transfer of mTEC-derived cell-surface antigen on CD8α+ DCs to promote tolerance to host antigens during homeostasis and allo-BMT. How cooperative antigen presentation between medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) occurs remains unknown. Perry et al. show that CD36, a scavenger receptor expressed on CD8α+ DCs, mediates acquisition and presentation of cell-surface antigens from mTECs for T cell receptor repertoire development and allo-tolerance during bone marrow transplantation.
N2 - The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells (mTECs) to bone marrow (BM) APCs is unknown. We report that antigen was primarily transferred from mTECs to CD8α+ dendritic cells (DCs) and showed that CD36, a scavenger receptor selectively expressed on CD8α+ DCs, mediated the transfer of cell-surface, but not cytoplasmic, antigens. The absence of CD8α+ DCs or CD36 altered thymic T cell selection, as evidenced by TCR repertoire analysis and the loss of allo-tolerance in murine allogeneic BM transplantation (allo-BMT) studies. Decreases in these DCs and CD36 expression in peripheral blood of human allo-BMT patients correlated with graft-versus-host disease. Our findings suggest that CD36 facilitates transfer of mTEC-derived cell-surface antigen on CD8α+ DCs to promote tolerance to host antigens during homeostasis and allo-BMT. How cooperative antigen presentation between medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) occurs remains unknown. Perry et al. show that CD36, a scavenger receptor expressed on CD8α+ DCs, mediates acquisition and presentation of cell-surface antigens from mTECs for T cell receptor repertoire development and allo-tolerance during bone marrow transplantation.
AB - The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells (mTECs) to bone marrow (BM) APCs is unknown. We report that antigen was primarily transferred from mTECs to CD8α+ dendritic cells (DCs) and showed that CD36, a scavenger receptor selectively expressed on CD8α+ DCs, mediated the transfer of cell-surface, but not cytoplasmic, antigens. The absence of CD8α+ DCs or CD36 altered thymic T cell selection, as evidenced by TCR repertoire analysis and the loss of allo-tolerance in murine allogeneic BM transplantation (allo-BMT) studies. Decreases in these DCs and CD36 expression in peripheral blood of human allo-BMT patients correlated with graft-versus-host disease. Our findings suggest that CD36 facilitates transfer of mTEC-derived cell-surface antigen on CD8α+ DCs to promote tolerance to host antigens during homeostasis and allo-BMT. How cooperative antigen presentation between medullary thymic epithelial cells (mTECs) and dendritic cells (DCs) occurs remains unknown. Perry et al. show that CD36, a scavenger receptor expressed on CD8α+ DCs, mediates acquisition and presentation of cell-surface antigens from mTECs for T cell receptor repertoire development and allo-tolerance during bone marrow transplantation.
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